التفاصيل البيبلوغرافية
| العنوان: |
Improved access to 2-O-monobenzyl ethers of β-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis |
| المؤلفون: |
Masurier, Nicolas1, Estour, François1, Lefèvre, Bertrand2, Brasme, Bernard2, Masson, Patrick3, Lafont, Olivier4 olivierlafont@wanadoo.fr |
| المصدر: |
Carbohydrate Research. May2006, Vol. 341 Issue 7, p935-940. 6p. |
| مصطلحات موضوعية: |
*BENZYLAMINOPURINE, *ENZYME inhibitors, *ORGANIC compounds, *CATALYSTS |
| مستخلص: |
Abstract: A comparative study of reaction conditions was performed for the synthesis of a 2-O-monobenzyl ether of cyclomaltoheptaose (β-CD). Optimal conditions involved sodium ethoxide in Me2SO and benzyl bromide. The methodology was extended to the preparation of various 2I-O-iodobenzyl and 2I-O-carboxymethylbenzyl derivatives of β-CD including a 3-carboxymethyl-4-iodobenzyl derivative of interest as precursor of an enzyme mimic to degrade the organophosphoryl ester diethyl 4-nitrophenyl phosphate (paraoxon). [Copyright &y& Elsevier] |
| قاعدة البيانات: |
Academic Search Index |
