دورية أكاديمية
Dynamics of Serum Thymidine Kinase 1 at the First Cycle of Neoadjuvant Chemotherapy Predicts Outcome of Disease in Estrogen-Receptor-Positive Breast Cancer
| العنوان: | Dynamics of Serum Thymidine Kinase 1 at the First Cycle of Neoadjuvant Chemotherapy Predicts Outcome of Disease in Estrogen-Receptor-Positive Breast Cancer |
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| المؤلفون: | Bernhard Tribukait |
| المصدر: | Cancers, Vol 13, Iss 21, p 5442 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | circulating thymidine kinase 1, cell loss, biomarker, early treatment response, breast cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Pathologic complete response (pCR) predicts the long-term outcome of neoadjuvantly treated (NAC) breast cancer (BC) but is reached in p = 0.005), and DFS was 90.7% and 68% (p = 0.006), respectively. Thus, the response of sTK1 at the first cycle of chemotherapy could be used both as an early biomarker for the guidance of chemotherapy and for the study of inherent tumor chemo-sensitivity, which could predict long-term outcome prior to therapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 13215442 2072-6694 |
| العلاقة: | https://www.mdpi.com/2072-6694/13/21/5442Test; https://doaj.org/toc/2072-6694Test |
| DOI: | 10.3390/cancers13215442 |
| الوصول الحر: | https://doaj.org/article/43f23180dbdf4735be547d759721b756Test |
| رقم الانضمام: | edsdoj.43f23180dbdf4735be547d759721b756 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13215442 20726694 |
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| DOI: | 10.3390/cancers13215442 |