نتائج البحث

1

First‐line pembrolizumab vs chemotherapy in metastatic non‐small‐cell lung cancer: KEYNOTE‐024 Japan subset*

المصدر: Cancer Science
Cancer Sci

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, non‐small‐cell lung carcinoma, Pembrolizumab, Kaplan-Meier Estimate, Gastroenterology, Deoxycytidine, B7-H1 Antigen, Carboplatin, 0302 clinical medicine, Antineoplastic Agents, Immunological, Japan, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Anaplastic Lymphoma Kinase, Neoplasm Metastasis, Aged, 80 and over, Cross-Over Studies, Hazard ratio, General Medicine, Middle Aged, PD-L1 protein, Progression-Free Survival, Oncology, 030220 oncology & carcinogenesis, non-small-cell lung carcinoma, Carcinoma, Squamous Cell, Female, Original Article, Non small cell, pembrolizumab, Adult, medicine.medical_specialty, Paclitaxel, First line, Pemetrexed, Antibodies, Monoclonal, Humanized, Drug Administration Schedule, 03 medical and health sciences, Drug Therapy, Clinical Research, Internal medicine, medicine, Confidence Intervals, Humans, Lung cancer, Adverse effect, PD‐L1 protein, Aged, Chemotherapy, business.industry, Genes, erbB-1, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Confidence interval, Retraction, 030104 developmental biology, treatment outcome, Cisplatin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692f872031566a6ba7ec9528f7d1191Test
https://doi.org/10.1111/cas.15144Test

2

Impact of tumor microenvironment on the efficacy of epidermal growth factor receptor‐tyrosine kinase inhibitors in patients withEGFR‐mutant non‐small cell lung cancer

المؤلفون: Jun Oyanagi, Tetsuya Watanabe, Koichi Ogawa, Mitsuru Fukui, Hiroyasu Kaneda, Tomoya Kawaguchi, Yasuhiro Koh, Yoshiya Matsumoto, Tomohiro Suzumura, Tatsuo Kimura, Shigeki Mitsuoka, Kenji Sawa, Nobuyuki Yamamoto, Motohiro Izumi, Kazuhisa Asai

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, epidermal growth factor receptor tyrosine kinase inhibitor, Cancer Research, Lung Neoplasms, Cell, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Japan, Carcinoma, Non-Small-Cell Lung, Tumor Microenvironment, Medicine, Epidermal growth factor receptor, Aged, 80 and over, education.field_of_study, biology, Kinase, General Medicine, Middle Aged, ErbB Receptors, Treatment Outcome, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Immunohistochemistry, Original Article, Female, Programmed cell death 1 ligand 2, non‐small cell lung cancer, Adult, medicine.medical_specialty, CD8 Antigens, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Clinical Research, Internal medicine, Humans, Lung cancer, education, Protein Kinase Inhibitors, Aged, Retrospective Studies, Tumor microenvironment, business.industry, Original Articles, programmed cell death‐1 ligand‐1, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, programmed cell death‐1 ligand‐2, Survival Analysis, 030104 developmental biology, Mutation, biology.protein, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb74ba3d7bb8d4caf8b67643a7c49790Test
https://doi.org/10.1111/cas.14156Test

3

Phase I study of the antiprogrammed cell death-1 Ab spartalizumab (PDR001) in Japanese patients with advanced malignancies

المؤلفون: Scott Cameron, Ayako Mitsuma, Yoichi Naito, Tomoya Shimokata, Yuichi Ando, Takeshi Tajima, Kae Ishihara, Nobuaki Matsubara, Yoshinori Imamura, Hironobu Minami, Kota Tokushige, Toshihiko Doi, Naomi Kiyota, Masanori Toyoda

المصدر: Cancer Science

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Antibodies, Monoclonal, Humanized, Gastroenterology, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Pharmacokinetics, Japan, Clinical Research, Neoplasms, Internal medicine, medicine, Maculopapular rash, Humans, Adverse effect, Immune Checkpoint Inhibitors, Aged, maximum tolerated dose, Dose-Response Relationship, Drug, business.industry, clinical trial, Original Articles, General Medicine, Middle Aged, medicine.disease, Discontinuation, Clinical trial, 030104 developmental biology, Transitional cell carcinoma, Oncology, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Toxicity, humanized monoclonal antibody, Female, Original Article, immunotherapy, medicine.symptom, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db60d64d2ef3d78d42de85360ea1f805Test
http://www.lib.kobe-u.ac.jp/handle_kernel/90007885Test

4

Limitations and benefits of FDG‐PET/CT in NF1 patients with nerve sheath tumors: A cross‐sectional/longitudinal study

المؤلفون: Kunihiro Ikuta, Yoshihiro Nishida, Hiroshi Koike, Hiroshi Urakawa, Shiro Imagama, Kan Ito, Tomohisa Sakai, Shinji Ito

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Longitudinal study, Carcinogenesis, Kaplan-Meier Estimate, Nerve sheath, Nerve Sheath Neoplasms, Malignant transformation, 0302 clinical medicine, Positron Emission Tomography Computed Tomography, Medicine, Longitudinal Studies, Prospective Studies, Child, Benignity, Thyroid, SUVmax, General Medicine, Middle Aged, Prognosis, Magnetic Resonance Imaging, medicine.anatomical_structure, Oncology, natural history, 030220 oncology & carcinogenesis, Original Article, Female, Fdg pet ct, Radiology, Adult, medicine.medical_specialty, Neurofibromatosis 1, Adolescent, Standardized uptake value, Malignancy, Young Adult, 03 medical and health sciences, MPNST, Clinical Research, Fluorodeoxyglucose F18, Humans, Aged, Neurofibroma, Plexiform, business.industry, Original Articles, medicine.disease, PET, Cross-Sectional Studies, 030104 developmental biology, ROC Curve, Feasibility Studies, business, plexiform neurofibroma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26271d1254a94797ac15077b33004b8Test
https://doi.org/10.1111/cas.14802Test

5

Eosinophil prognostic scores for patients with head and neck squamous cell carcinoma treated with nivolumab

المؤلفون: Shigenori Kadowaki, Michi Sawabe, Michihiko Sone, Hoshino Terada, Hidenori Suzuki, Nobuhiro Hanai, Daisuke Nishikawa, Shintaro Beppu

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Immune checkpoint inhibitors, head and neck squamous cell carcinoma, 03 medical and health sciences, Leukocyte Count, 0302 clinical medicine, Antineoplastic Agents, Immunological, Clinical Research, Internal medicine, Programmed cell death 1, medicine, Biomarkers, Tumor, Humans, Aged, Retrospective Studies, nivolumab, biology, business.industry, Squamous Cell Carcinoma of Head and Neck, Hazard ratio, prognostic factors, Retrospective cohort study, General Medicine, Immunotherapy, Eosinophil, Middle Aged, medicine.disease, Prognosis, Head and neck squamous-cell carcinoma, Eosinophils, 030104 developmental biology, medicine.anatomical_structure, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, biology.protein, Original Article, Female, immunotherapy, Nivolumab, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a17b53efea0bddea889dd99dba72a92Test
http://europepmc.org/articles/PMC7780035Test

6

Tumor-derived exosomal proteins as diagnostic biomarkers in non-small cell lung cancer

المؤلفون: Li Xie, Ning Wang, Xianrang Song, Xingguo Song, Linlin Xue, Limin Niu

المصدر: Cancer Science

مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, alpha-2-HS-Glycoprotein, Exosomes, 0302 clinical medicine, Carcinoembryonic antigen, Carcinoma, Non-Small-Cell Lung, Stage (cooking), Genetics, Genomics, and Proteomics, Aged, 80 and over, Extracellular Matrix Proteins, education.field_of_study, biology, General Medicine, Middle Aged, Neoplasm Proteins, 030220 oncology & carcinogenesis, Original Article, Female, non‐small cell lung cancer, tumor‐derived exosomes, Adult, medicine.medical_specialty, Sensitivity and Specificity, 03 medical and health sciences, Extracellular matrix protein 1, Microscopy, Electron, Transmission, Internal medicine, Biomarkers, Tumor, medicine, Humans, education, Lung cancer, Aged, extracellular matrix protein 1, Receiver operating characteristic, diagnostic marker, business.industry, Cancer, Original Articles, medicine.disease, Microvesicles, Carcinoembryonic Antigen, respiratory tract diseases, 030104 developmental biology, biology.protein, alpha‐2‐HS‐glycoprotein, business, alpha-2-HS-glycoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f7f0ad57848b792094a09d61c205eeTest
https://doi.org/10.1111/cas.13862Test

7

Five‐year safety and efficacy data from a phase Ib study of nivolumab and chemotherapy in advanced non‐small‐cell lung cancer

المؤلفون: Noboru Yamamoto, Yuichiro Ohe, Hiroshi Nokihara, Yutaka Fujiwara, Takanori Yamamoto, Yasushi Goto, Shintaro Kanda, Tomohide Tamura, Hidehito Horinouchi

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, Docetaxel, chemotherapy, Deoxycytidine, Carboplatin, chemistry.chemical_compound, Basic and Clinical Immunology, 0302 clinical medicine, Maintenance therapy, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, non‐small‐cell lung cancer, General Medicine, Middle Aged, Progression-Free Survival, Bevacizumab, Treatment Outcome, Pemetrexed, 030220 oncology & carcinogenesis, Original Article, Female, Nivolumab, medicine.drug, combination drug therapy, Adult, medicine.medical_specialty, Paclitaxel, programmed cell death 1 receptor, 03 medical and health sciences, Internal medicine, medicine, Humans, Lung cancer, Aged, nivolumab, business.industry, Original Articles, medicine.disease, Gemcitabine, 030104 developmental biology, chemistry, Cisplatin, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b25386fae4a7d98e2140b98c3a05adTest
https://doi.org/10.1111/cas.14410Test

8

Efficacy and safety of nivolumab in Japanese patients with uterine cervical cancer, uterine corpus cancer, or soft tissue sarcoma: Multicenter, open‐label phase 2 trial

المؤلفون: Noriyuki Katsumata, Hiroyuki Nomura, Koji Matsumoto, Kenji Tamura, Shunji Takahashi, Hirofumi Mukai, Hironobu Minami, Kosei Hasegawa

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Programmed Cell Death 1 Receptor, Phases of clinical research, B7-H1 Antigen, 0302 clinical medicine, Japan, Clinical endpoint, Medicine, Prospective Studies, programmed death‐1, Infusions, Intravenous, programmed death-1, Cervical cancer, Soft tissue sarcoma, Sarcoma, General Medicine, Middle Aged, Progression-Free Survival, uterine corpus cancer, soft tissue sarcoma, 030220 oncology & carcinogenesis, Uterine Neoplasms, Toxicity, Original Article, Female, Microsatellite Instability, Nivolumab, Adult, medicine.medical_specialty, Antineoplastic Agents, Drug Administration Schedule, 03 medical and health sciences, Clinical Research, Internal medicine, Humans, Aged, nivolumab, business.industry, Uterus, Cancer, Original Articles, medicine.disease, Survival Analysis, Immune checkpoint, 030104 developmental biology, Neoplasm Recurrence, Local, business, uterine cervical cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ba2345f47871fd2955f5bf14d9dbfeTest
https://doi.org/10.1111/cas.14148Test

9

Human equilibrative nucleoside transporter-1 expression is a predictor in patients with resected pancreatic cancer treated with adjuvant S-1 chemotherapy

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, JASPAC 01, medicine.medical_treatment, pancreatic cancer, Equilibrative nucleoside transporter 1, 0302 clinical medicine, Medicine, Randomized Controlled Trials as Topic, Aged, 80 and over, biology, Clinical Trials, Phase I as Topic, Hazard ratio, General Medicine, Middle Aged, Prognosis, Gene Expression Regulation, Neoplastic, Drug Combinations, Treatment Outcome, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Biomarker (medicine), biomarker, Female, Original Article, human equilibrative nucleoside transporter‐1, Adjuvant, medicine.drug, Adult, medicine.medical_specialty, Antimetabolites, Antineoplastic, Equilibrative Nucleoside Transporter 1, 03 medical and health sciences, Pancreatectomy, Clinical Research, Internal medicine, Pancreatic cancer, Dihydropyrimidine dehydrogenase, Biomarkers, Tumor, Humans, Dihydrouracil Dehydrogenase (NADP), Aged, Retrospective Studies, Tegafur, Chemotherapy, business.industry, dihydropyrimidine dehydrogenase, Original Articles, medicine.disease, Survival Analysis, Gemcitabine, Pancreatic Neoplasms, Oxonic Acid, 030104 developmental biology, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fde3ba7ac349252216c69c5240adf7Test
https://pubmed.ncbi.nlm.nih.gov/31778273Test

10

Potential utility of a longitudinal relative dose intensity of molecularly targeted agents in phase 1 dose‐finding trials

المؤلفون: Kenji Tamura, Akihiro Hirakawa, Yasuhiro Fujiwara, Yumiko Kobayashi, Fumie Kinoshita, Kan Yonemori, Asuka Kawachi, Pamela Jo Harris, Hitomi Sumiyoshi Okuma, Larry Rubinstein, Naoko Takebe

المصدر: Cancer Science

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, relative dose intensity, Antineoplastic Agents, recommended phase 2 dose, 03 medical and health sciences, Dose finding, Young Adult, 0302 clinical medicine, phase 1 trial, Clinical Research, Internal medicine, Neoplasms, medicine, Humans, Longitudinal Studies, Molecular Targeted Therapy, Aged, Response rate (survey), Aged, 80 and over, Lower grade, Toxicity data, maximum tolerated dose, Clinical Trials, Phase I as Topic, business.industry, Disease progression, Phase 1 trials, General Medicine, Original Articles, Middle Aged, Dose intensity, Surgery, 030104 developmental biology, molecularly targeted agent, Treatment Outcome, 030220 oncology & carcinogenesis, Toxicity, Disease Progression, Original Article, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b842b36a941406871539f21538246817Test
http://europepmc.org/articles/PMC5765308Test

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