Abstract P5-14-05: Improved Survival of Patients with Primary Distant Metastatic Breast Cancer in the Period of 1995 — 2007
| العنوان: | Abstract P5-14-05: Improved Survival of Patients with Primary Distant Metastatic Breast Cancer in the Period of 1995 — 2007 |
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| المؤلفون: | Koop Bosscha, Vcg Tjan-Heijnen, L.V. van de Poll-Franse, Ac. Voogd, der Loo M van der Heiden-van, Miranda F. Ernst, Esther Bastiaannet, J. Ruiterkamp, L. de Munck |
| المصدر: | Cancer Research. 70:P5-14 |
| بيانات النشر: | American Association for Cancer Research (AACR), 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Oncology, Cancer Research, medicine.medical_specialty, business.industry, Breast surgery, medicine.medical_treatment, Improved survival, Cancer, Retrospective cohort study, Disease, medicine.disease, Metastatic breast cancer, Cancer registry, Breast cancer, Internal medicine, medicine, business |
| الوصف: | Introduction During the last fifteen years, important changes have taken place concerning the sy stemic treatment for patients with metastasized breast cancer. It would be interesting to know whether these improvements have also taken place patients with primary distant metastatic breast cancer. Additionally, several retrospective studies have shown an improvement in overall survival in patients who have received breast surgery. Therefore, we also analyzed the role of surgical resection of the primary breast tumor. Methods According to the database of the Dutch Cancer Registry 7,358 (5.0%) patients were diagnosed with primary distant metastases between 1997 and 2007. To establish whether improvement of prognosis had taken place, patients were divided into three periods of diagnosis, based on the year of diagnosis of their disease; 1995-1999, 2000-2003 and 2004-2007. The follow-up of these patients was completed until January 1, 2009. Results The median survival was 1.42 years for patients diagnosed in the period 1995-1999, 1.56 years in the period 2000-2003 and 2.0 years in the period 2004-2007. Only the difference between the periods 2000-2003 and 2004-2007 was statistically significant (P An improvement of six months is seen in the median survival of patients with primary distant metastatic breast cancer, resulting in a median survival of two years in 2007. Maybe, if surgery was more performed in the most recent time period, the improvement of the median survival was even better. However, it seems reasonable to argue that this improvement is due to new developments in systemic treatment. Figures available in online version. Citation Information: Cancer Res 2010;70(24 Suppl):Abstract nr P5-14-05. |
| تدمد: | 1538-7445 0008-5472 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::a1b475030afb11bb397b7878fed965a2Test https://doi.org/10.1158/0008-5472.sabcs10-p5-14-05Test |
| رقم الانضمام: | edsair.doi...........a1b475030afb11bb397b7878fed965a2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15387445 00085472 |
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