نتائج البحث

1

Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7–H4 expression through the MEK/ERK signaling pathway

المؤلفون: Bin Zhou, Moli Huang, Ningyue Zhang, Lei Zhang, Fengying Wu, Zhiming Zhao, Shaomu Chen, Yali Chen, Anqi Li

المصدر: Cancer Letters. 485:14-26

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Lung Neoplasms, MAP Kinase Signaling System, medicine.medical_treatment, CD8-Positive T-Lymphocytes, Receptor, IGF Type 1, Mice, 03 medical and health sciences, Insulin-like growth factor, 0302 clinical medicine, Cell Line, Tumor, Immune Tolerance, medicine, Animals, Humans, Cytotoxic T cell, Lung cancer, Aged, Insulin-like growth factor 1 receptor, Aged, 80 and over, Chemistry, Middle Aged, V-Set Domain-Containing T-Cell Activation Inhibitor 1, medicine.disease, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, body regions, 030104 developmental biology, Oncology, Tumor progression, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d9197cad7c5256237276c3d1dc6571Test
https://doi.org/10.1016/j.canlet.2020.04.013Test

2

SPIN1 triggers abnormal lipid metabolism and enhances tumor growth in liver cancer

المؤلفون: Ying Yuan, Zixian Liu, Yujun Chen, Huihui Zhang, Hongfeng Yuan, Man Zhao, Lei Liu, Jinyan Feng, Xiaodong Zhang, Guang Yang, Jiapei Wang, Haolin Yun, Yanan Bu

المصدر: Cancer Letters. 470:54-63

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Cell Cycle Proteins, medicine.disease_cause, Mice, 0302 clinical medicine, Lipid droplet, Protein Isoforms, Promoter Regions, Genetic, Aged, 80 and over, Tissue microarray, Chemistry, Liver Neoplasms, Hep G2 Cells, Middle Aged, Up-Regulation, Fatty Acid Synthase, Type I, Gene Expression Regulation, Neoplastic, Liver, Oncology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Female, Sterol Regulatory Element Binding Protein 1, Liver cancer, Microtubule-Associated Proteins, Signal Transduction, Adult, Carcinoma, Hepatocellular, 03 medical and health sciences, medicine, Animals, Hepatectomy, Humans, Aged, Cell Proliferation, Lipogenesis, Cancer, Lipid metabolism, Phosphoproteins, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, 030104 developmental biology, Tissue Array Analysis, Cancer research, Spindle organization, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7911daffd040766ceca8910672c4b27fTest
https://doi.org/10.1016/j.canlet.2019.11.032Test

3

RACK1 promotes the invasive activities and lymph node metastasis of cervical cancer via galectin-1

المؤلفون: Daochuan He, Ran Zhao, Yuanyuan Ruan, Lei Chang, Hao Wu, Lan Hu, Mengzhen Kuang, Xin Wu, Bo Liu, Shushu Song, Jianxin Gu, Xinying Guo, Ling Xu, Anqi Yan, Lan Wang

المصدر: Cancer Letters. 469:287-300

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06c4aad93689cef40a2c4154a80d2bdTest
https://doi.org/10.1016/j.canlet.2019.11.002Test

4

DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma

المؤلفون: Wei Ting Gu, Jinyan Huang, Yu Wang, Yong Zhi Zheng, Xin Yi Liu, Zhe Bao Wu, Yan Ting Liu, Hong Yao, Xun Zhang, Qiu Fen Zhang, Yong Xu Wei, Jian Zhang, Hao Tang, Han Bing Shang, Yong Zhang

المصدر: Cancer Letters. 459:135-144

مصطلحات موضوعية: Adenoma, Adult, Male, 0301 basic medicine, Cancer Research, Down-Regulation, Mice, Nude, Mechanistic Target of Rapamycin Complex 2, mTORC1, Mechanistic Target of Rapamycin Complex 1, DEPTOR, mTORC2, Mice, 03 medical and health sciences, 0302 clinical medicine, Autophagy, Animals, Humans, Pituitary Neoplasms, Prolactinoma, Kinase activity, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, Cell Proliferation, biology, Cell growth, Chemistry, Intracellular Signaling Peptides and Proteins, Middle Aged, Rats, Ubiquitin ligase, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, Pituitary Gland, 030220 oncology & carcinogenesis, Dopamine Agonists, biology.protein, Cancer research, Heterografts, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d548c52f38a4094d08f3735b27f83aTest
https://doi.org/10.1016/j.canlet.2019.05.043Test

5

RETRACTED: HIF-1α mediates tumor-nerve interactions through the up-regulation of GM-CSF in pancreatic ductal adenocarcinoma

المؤلفون: Jihui Hao, Liangliang Wu, Chungen Lan, Xiuchao Wang, Rujiang Jia, Bodong Zhou, Mingxiao Lang, Zengxun Li, Haotian Wang, Xin Li, Yan Sun, He Ren, Tiansuo Zhao, Hongwei Wang

المصدر: Cancer Letters. 453:10-20

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Pancreatic ductal adenocarcinoma, endocrine system diseases, Perineural invasion, Mice, Nude, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, Animals, Humans, Neoplasm Invasiveness, Secretion, Peripheral Nerves, Pathological, Aged, Neoplasm Staging, Tumor microenvironment, Gene knockdown, Granulocyte-Macrophage Colony-Stimulating Factor, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, digestive system diseases, Up-Regulation, Blockade, Pancreatic Neoplasms, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Schwann Cells, Carcinoma, Pancreatic Ductal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74849628aeb0140481dce64153e3269Test
https://doi.org/10.1016/j.canlet.2019.03.036Test

6

IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells

المؤلفون: Priscila Santos Scheucher, João Agostinho Machado-Neto, Eduardo Magalhães Rego, Anne J. Ridley, Bruna Alves Fenerich, Ana Paula Nunes Rodrigues Alves, Belinda Pinto Simões, Fabiola Traina, Jaqueline Cristina Fernandes, Juan L Coelho-Silva

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, Adult, Cancer Research, Cell signaling, Antineoplastic Agents, Apoptosis, APOPTOSE, Pyrogallol, Jurkat cells, Receptor, IGF Type 1, 03 medical and health sciences, Jurkat Cells, Young Adult, 0302 clinical medicine, Tumor Cells, Cultured, Cytotoxic T cell, Humans, Molecular Targeted Therapy, Protein kinase B, PI3K/AKT/mTOR pathway, Insulin-like growth factor 1 receptor, Aged, Cell Proliferation, Sulfonamides, Chemistry, TOR Serine-Threonine Kinases, Cell Cycle, Imidazoles, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Pyrazines, Cancer research, Insulin Receptor Substrate Proteins, Mitogen-Activated Protein Kinases, Phosphatidylinositol 3-Kinase, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef852223ee9b40c688473781f8b960aeTest
https://pubmed.ncbi.nlm.nih.gov/31042587Test

7

Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma

المؤلفون: Mercedes del Rio-Moreno, Manuel Rodríguez-Perálvarez, M. Trinidad Moreno-Montilla, Juan M. Jiménez-Vacas, Irene Gómez-Luque, Juan L López-Cánovas, Justo P. Castaño, Manuel D. Gahete, Víctor Amado, Raúl M. Luque, Helena García-Fernandez, Fernando L-López, Rubén Nogueiras, Ruben Ciria, Javier Briceño, Marcos F. Fondevila, Marina E. Sánchez-Frías, Manuel de la Mata

المصدر: Cancer letters. 496

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Adult, Male, Cancer Research, Carcinoma, Hepatocellular, Splicing Factor 3B Subunit 1, Mice, Nude, Apoptosis, Biology, 03 medical and health sciences, Splicing factor, Mice, 0302 clinical medicine, Cell Movement, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Gene silencing, Animals, Humans, Aged, Cell Proliferation, Retrospective Studies, CD24, Liver Neoplasms, Cancer, Middle Aged, medicine.disease, Phosphoproteins, Prognosis, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Survival Rate, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, RNA splicing, Cancer research, Female, RNA Splicing Factors, Signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fbe269fd27a64b4881ac2347f0b3bdTest
https://pubmed.ncbi.nlm.nih.gov/33038489Test

8

Epigenetic silencing of chemokine CCL2 represses macrophage infiltration to potentiate tumor development in small cell lung cancer

المؤلفون: Ziling Liu, Guojiang Chen, Simeng Wei, Zhihong Wang, Yang Zheng

المصدر: Cancer letters. 499

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Chemokine, Indoles, Lung Neoplasms, Carcinogenesis, Epigenesis, Genetic, Histones, Mice, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, Lung, Chemokine CCL2, biology, Chemistry, EZH2, Middle Aged, Enhancer Elements, Genetic, Oncology, 030220 oncology & carcinogenesis, DNA methylation, Female, medicine.drug, Adult, DNA (Cytosine-5-)-Methyltransferase 1, Adolescent, Pyridones, Decitabine, CCL2, 03 medical and health sciences, Young Adult, Phagocytosis, medicine, Animals, Humans, Enhancer of Zeste Homolog 2 Protein, Epigenetics, Aged, Innate immune system, DNA Methylation, Small Cell Lung Carcinoma, Xenograft Model Antitumor Assays, respiratory tract diseases, 030104 developmental biology, Tissue Array Analysis, Cancer research, DNMT1, biology.protein, CpG Islands

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96af8cacb388be39398e4c3f44173d5Test
https://pubmed.ncbi.nlm.nih.gov/33253790Test

9

CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance

المؤلفون: Lejian Jiang, Shihang Xue, Shuang Mei, Lanlan Hui, Wenfang Meng, Yang Yang, Min-Xin Guan, Ye Chen, Hu Xiaojia

المصدر: Cancer Letters. 425:1-12

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc33f72290fc52e34500521e8096b3f4Test
https://doi.org/10.1016/j.canlet.2018.03.024Test

10

All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase

المؤلفون: Cheng Chen, Kailin Yu, Zongru Jiang, Fengming Zou, Juan Liu, Li Wang, Aoli Wang, Wenchao Wang, Jing Liu, Qingsong Liu, Wenliang Wang

المصدر: Cancer letters. 473

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, DNA Repair, Retinoic acid, Apoptosis, chemistry.chemical_compound, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Mitotic catastrophe, media_common, Chemistry, Gene Expression Regulation, Leukemic, Myeloid leukemia, Drug Synergism, Middle Aged, Leukemia, Myeloid, Acute, Oncology, Tandem Repeat Sequences, 030220 oncology & carcinogenesis, Child, Preschool, embryonic structures, Drug, Adult, DNA damage, media_common.quotation_subject, Primary Cell Culture, Down-Regulation, Mitosis, Tretinoin, Irinotecan, 03 medical and health sciences, In vivo, Cell Line, Tumor, Animals, Humans, neoplasms, Protein Kinase Inhibitors, Aged, organic chemicals, Xenograft Model Antitumor Assays, biological factors, In vitro, 030104 developmental biology, fms-Like Tyrosine Kinase 3, Checkpoint Kinase 1, Cancer research, Topoisomerase I Inhibitors, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8d3e40407d09d53084a33a3c8e4e0bTest
https://pubmed.ncbi.nlm.nih.gov/31904486Test

تنقيح النتائج