نتائج البحث

1

A phase 2 clinical trial assessing the efficacy and safety of pembrolizumab and radiotherapy in patients with metastatic triple‐negative breast cancer

المؤلفون: Lizza Lebron-Zapata, Jessica Flynn, Samantha A. Dunn, Christopher A. Barker, Alice Y. Ho, Brittany Arnold, Alessandro D'Agnolo, Simon N. Powell, Cindy Kallman, Hannah Y Wen, Heather L. McArthur, Ayca Gucalp, Zishuo I. Hu, Zhigang Zhang

المصدر: Cancer. 126:850-860

مصطلحات موضوعية: Adult, Oncology, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Phases of clinical research, Dermatitis, Triple Negative Breast Neoplasms, Kaplan-Meier Estimate, Pembrolizumab, Antibodies, Monoclonal, Humanized, Cohort Studies, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Breast cancer, Lymphopenia, Internal medicine, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Adverse effect, Fatigue, Aged, Radiotherapy, business.industry, Common Terminology Criteria for Adverse Events, Chemoradiotherapy, Middle Aged, medicine.disease, Treatment Outcome, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Female, business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d5c898e9ad0fa0f0c3930aa6e73600Test
https://doi.org/10.1002/cncr.32599Test

2

High neutrophil‐to‐lymphocyte ratio (NLR) is associated with treatment failure and death in patients who have melanoma treated with PD‐1 inhibitor monotherapy

المؤلفون: Charlotte E. Ariyan, Jessica M. Sta.Cruz, Michael A. Postow, Richard Ferraro, Jessica Flynn, Katherine S. Panageas, Edmund K. Bartlett, Daniel G. Coit

المصدر: Cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727cec8509d491c46a2a16f9eaf14db9Test
https://doi.org/10.1002/cncr.32506Test

3

Site‐specific response patterns, pseudoprogression, and acquired resistance in patients with melanoma treated with ipilimumab combined with anti–PD‐1 therapy

المؤلفون: Camelia Quek, Serigne Lo, María Jesús González González, Alexander M. Menzies, Georgina V. Long, Matteo S. Carlino, Ines Pires da Silva

المصدر: Cancer. 126:86-97

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e3e18e12a7350cf377ff397b00c4a7Test
https://doi.org/10.1002/cncr.32522Test

4

Health care utilization and steroid‐refractory toxicities from immune checkpoint inhibitors

المؤلفون: Stacie B. Dusetzina, Elizabeth J. Davis, Henry T. Quach, Jeffrey A. Sosman, Laura X. Wang, Douglas B. Johnson, Nikil V. Moodabigil

المصدر: Cancer

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Drug-Related Side Effects and Adverse Reactions, Combination therapy, Programmed Cell Death 1 Receptor, Drug Resistance, Ipilimumab, Pembrolizumab, Antibodies, Monoclonal, Humanized, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, CTLA-4 Antigen, 030212 general & internal medicine, Adverse effect, Glucocorticoids, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Incidence (epidemiology), Middle Aged, Patient Acceptance of Health Care, medicine.disease, Progression-Free Survival, Infliximab, Nivolumab, Oncology, 030220 oncology & carcinogenesis, Disease Progression, Female, business, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441069edc41d4157073d3f2cee899993Test
https://doi.org/10.1002/cncr.32542Test

5

Germline mutations of renal cancer predisposition genes and clinical relevance in Chinese patients with sporadic, early‐onset disease

المؤلفون: Junlong Wu, Dingwei Ye, Hongkai Wang, Hailiang Zhang, Guohai Shi, Maria J. Merino, Yao Zhu, Youfeng Yang, W. Marston Linehan, Christopher J. Ricketts, Hualei Gan

المصدر: Cancer

مصطلحات موضوعية: Adult, Male, Cancer Research, Adolescent, Angiomyolipoma, Disease, Article, Tuberous Sclerosis Complex 1 Protein, Germline, Fumarate Hydratase, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Asian People, Tuberous Sclerosis Complex 2 Protein, Humans, Medicine, Genetic Predisposition to Disease, Clinical significance, 030212 general & internal medicine, Family history, Carcinoma, Renal Cell, Gene, Cyclin-Dependent Kinase Inhibitor p16, Germ-Line Mutation, BRCA2 Protein, Genetics, BAP1, business.industry, Tumor Suppressor Proteins, High-Throughput Nucleotide Sequencing, Sequence Analysis, DNA, Kidney Neoplasms, Oncology, 030220 oncology & carcinogenesis, Female, Personalized medicine, business, Ubiquitin Thiolesterase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b9b8b74e784a95ee93e946d2197496Test
https://doi.org/10.1002/cncr.31908Test

6

Tolerance and efficacy of BRAF plus MEK inhibition in patients with melanoma who previously have received programmed cell death protein 1‐based therapy

المؤلفون: Angelica Bialczak, Alexander N. Shoushtari, Daniel Y. Wang, Jeewon Chon, Ryan J. Sullivan, Meghan J. Mooradian, Cathy Yi Xia, Douglas B. Johnson, Alexander M. Menzies, Kelly Abbate, Karim R. Saab

المصدر: Cancer

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Pyridones, Programmed Cell Death 1 Receptor, Population, Pyrimidinones, Article, Tertiary Care Centers, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Oximes, Humans, Medicine, 030212 general & internal medicine, education, Adverse effect, Melanoma, Protein Kinase Inhibitors, neoplasms, Aged, Dose Modification, Aged, 80 and over, Trametinib, education.field_of_study, business.industry, Australia, Imidazoles, Dabrafenib, Middle Aged, medicine.disease, Survival Analysis, United States, Discontinuation, Regimen, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5019125a85fa9b67884971a23cad8af5Test
https://doi.org/10.1002/cncr.31889Test

7

A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas

المؤلفون: Andrew J. Wagner, Hans Gelderblom, Patrick Schöffski, Brian A. Van Tine, Rashmi Chugh, Kert Viele, Wenquan Wang, Axel Le Cesne, Susan C. Weil, Shreyaskumar Patel, Steven Attia, Jonathan C. Trent, John Heyburn, Robert G. Maki, Bartosz Chmielowski, Robin L. Jones, Sant P. Chawla

المصدر: Cancer
Cancer, 125(14), 2445-2454. WILEY

مصطلحات موضوعية: Male, Cancer Research, MORAb‐004, medicine.medical_treatment, Docetaxel, Gastroenterology, THERAPY, Deoxycytidine, Cohort Studies, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, 030212 general & internal medicine, tumor endothelial marker 1 (TEM-1), sarcomas, Aged, 80 and over, Hazard ratio, Sarcoma, Middle Aged, Progression-Free Survival, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Female, Original Article, ontuxizumab, Life Sciences & Biomedicine, medicine.drug, EXPRESSION, Adult, medicine.medical_specialty, Antimetabolites, Antineoplastic, Randomization, MORAb-004, Placebo, Antibodies, Monoclonal, Humanized, Soft Tissue and Bone Sarcoma, 03 medical and health sciences, Young Adult, Double-Blind Method, Antigens, CD, Antigens, Neoplasm, Internal medicine, medicine, PLUS DOCETAXEL, Biomarkers, Tumor, Humans, Aged, Chemotherapy, ENDOSIALIN, Science & Technology, business.industry, Original Articles, medicine.disease, Gemcitabine, Confidence interval, tumor endothelial marker 1 (TEM‐1), ANTIBODY, Disease Site, endosialin, business

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec138badfbcb532104f5a8da82963414Test
https://pubmed.ncbi.nlm.nih.gov/31034598Test

8

Objective physical and mental markers of self‐reported fatigue in women undergoing (neo)adjuvant chemotherapy for early‐stage breast cancer

المؤلفون: Joanne E. Mortimer, Arti Hurria, Carolyn E. Behrendt, Sarah Waliany, Joseph Chao, Christina M. Dieli-Conwright, Sunita K. Patel, Brian Tiep

المصدر: Cancer

مصطلحات موضوعية: Oncology, Cancer Research, Neuropsychological Tests, chemotherapy, Pittsburgh Sleep Quality Index, cancer‐related fatigue, Grip strength, 0302 clinical medicine, Surveys and Questionnaires, Antineoplastic Combined Chemotherapy Protocols, Medicine, Cancer-related fatigue, Chemokine CCL2, Fatigue, Depression (differential diagnoses), Chemokine CCL3, Depression, Middle Aged, Interleukin-12, Neoadjuvant Therapy, 3. Good health, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Original Article, Female, medicine.symptom, Adult, Chemokine CCL11, medicine.medical_specialty, Breast Neoplasms, Walk Test, Discipline, 03 medical and health sciences, breast cancer, physical function, Breast cancer, Internal medicine, Humans, Clinical Trials, Cyclophosphamide, Neoplasm Staging, Trail Making Test, business.industry, Cancer, Original Articles, medicine.disease, Clinical trial, Interleukin 1 Receptor Antagonist Protein, Doxorubicin, Linear Models, Self Report, Energy Metabolism, Sleep, business, Neurocognitive, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea658d2ccb9966856d7ae52230a0b12Test
https://doi.org/10.1002/cncr.30426Test

9

Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma

المؤلفون: Niramol Savaraj, Lynn G. Feun, Stephen P. Richman, Ying-Ying Li, Deukwoo Kwon, Beatrice L. Madrazo, Peter J. Hosein, Chunjing Wu, Paul J. Martin, Patricia D. Jones, Monica T. Garcia-Buitrago, Medhi Wangpaichitr

المصدر: Cancer

مصطلحات موضوعية: Sorafenib, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Carcinoma, Hepatocellular, Programmed Cell Death 1 Receptor, Phases of clinical research, Pembrolizumab, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, B7-H1 Antigen, Article, 03 medical and health sciences, Interferon-gamma, 0302 clinical medicine, Transforming Growth Factor beta, Internal medicine, Blood plasma, medicine, Humans, 030212 general & internal medicine, Prospective Studies, Adverse effect, Aged, Hepatitis, Aged, 80 and over, business.industry, Liver Neoplasms, Middle Aged, medicine.disease, Progression-Free Survival, Interleukin-10, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Toxicity, Disease Progression, Female, business, medicine.drug, Tomography, Emission-Computed

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89eb94a0ab4712d67c8ba39e030868aaTest
https://pubmed.ncbi.nlm.nih.gov/31251403Test

10

A critical analysis of prognostic factors in North American patients with human T-cell lymphotropic virus type-1-associated adult T-cell leukemia/lymphoma

المؤلفون: Gerald A. Soff, Jasmine Zain, William B. Solomon, Owen A. O'Connor, Jasotha Sanmugarajah, Govind Bhagat, Adrienne A. Phillips, David G. Savage, Iuliana Shapira, Bachir Alobeid, Robert D. Willim, Steven M. Horwitz, Venkatraman E. Seshan

المصدر: Cancer. 116:3438-3446

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6e14d11641d4a52a7a3973ff26fca1Test
https://doi.org/10.1002/cncr.25147Test

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