دورية أكاديمية

Histoenzymological Characteristics of the Heart Conduction System: Comparative Study with Left or Right Ventricle Afterload.

التفاصيل البيبلوغرافية
العنوان: Histoenzymological Characteristics of the Heart Conduction System: Comparative Study with Left or Right Ventricle Afterload.
المؤلفون: Tverskaya, M., Sukhoparova, V., Kadyrova, M., Klyuchikov, V., Bobrova, N.
المصدر: Bulletin of Experimental Biology & Medicine; Sep2013, Vol. 155 Issue 5, p618-621, 4p
مصطلحات موضوعية: HEART conduction system, LEFT heart ventricle, RIGHT heart ventricle, HEART ventricles, HEART failure, PHYSIOLOGY
مستخلص: Histoenzymological changes, indicating inhibition of the main metabolic processes, were found in the conduction cardiomyocytes of the left ventricle and ventricular septum in experimental stenosis of the aorta. The histoenzymological changes in the conduction system of both ventricles and ventricular septum were similar in experimental stenosis of the pulmonary artery and indicated primarily activation of glycolysis. The histoenzymological profi le of conduction cardiomyocytes differed little in cases when the increase of the pressure load was complicated or not complicated by the development of heart failure, particularly in pulmonary artery stenosis. The histoenzymological changes in the conduction system in response to increased afterload differed significantly from those in the contractile myocardium and correlated with the level of cellular functional activity and sensitivity to the regulatory and alterative exposure. These data attest to minor role of metabolic shifts in conduction cell injuries with increasing afterload, primarily, of the right ventricle. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00074888
DOI:10.1007/s10517-013-2209-y