التفاصيل البيبلوغرافية
| العنوان: |
Relationship between ganglion cell-inner plexiform layer and optic disc/retinal nerve fibre layer parameters in non-glaucomatous eyes. |
| المؤلفون: |
Yih-Chung Tham1,2, Cheung, Carol Y.1,2,3, Koh, Victor T.1,2, Ching-Yu Cheng1,2, Sidhartha, Elizabeth1, Strouthidis, Nicholas G.1,4, Wong, Tien Y.1,2, Tin Aung1,2 aung.tin@snec.com.sg |
| المصدر: |
British Journal of Ophthalmology. Dec2013, Vol. 97 Issue 12, p1592-1597. 6p. 1 Diagram, 4 Charts. |
| مصطلحات موضوعية: |
*OPHTHALMOLOGY, *OPTIC disc, *OPTIC nerve, *RETINA, *RETINAL ganglion cells, *OPTICAL coherence tomography |
| مستخلص: |
Aims To determine the relationship between macular ganglion cell-inner plexiform layer (GC-IPL) thickness and optic disc/retinal nerve fibre layer (RNFL) parameters in non-glaucomatous eyes measured by spectral-domain optical coherence tomography (SD-OCT). Methods 491 non-glaucomatous Chinese aged 40-80 years were recruited from a population-based study and underwent standardised ophthalmic examination. SD-OCT was used to measure GC-IPL thickness, optic disc parameters and RNFL thickness. Univariate and multiple linear regression analyses were performed to assess the association between GC-IPL and optic disc/RNFL parameters. Results In univariate analyses, all RNFL parameters and rim area were significantly correlated with all macular GC-IPL parameters ( p<0.001, r=0.12-0.56). In multiple regression analyses, after adjusting for age, gender, disc area, signal strength and axial length, average RNFL thickness ( per mm decrease) was most strongly correlated with average GC-IPL thickness (β=-0.30, standardised β=-0.499, p<0.001) compared with other optic disc/RNFL parameters. Conclusions Our study demonstrated only fair correlations between macular GC-IPL and optic disc/ RNFL parameters measured by SD-OCT. This information is important for further evaluation of macular GC-IPL thickness as an additional marker in detecting glaucomatous damage and progression. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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