Effects of immobilization and remobilization on the ankle joint in Wistar rats
| العنوان: | Effects of immobilization and remobilization on the ankle joint in Wistar rats |
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| المؤلفون: | Regina Inês Kunz, Gladson Ricardo Flor Bertolini, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Lígia Inez Silva, Josinéia Gresele Coradini |
| المصدر: | Brazilian Journal of Medical and Biological Research v.47 n.10 2014 Brazilian Journal of Medical and Biological Research Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC Brazilian Journal of Medical and Biological Research, Volume: 47, Issue: 10, Pages: 842-849, Published: 15 AUG 2014 Brazilian Journal of Medical and Biological Research, Vol 47, Iss 10, Pp 842-849 (2014) |
| بيانات النشر: | FapUNIFESP (SciELO), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Cartilage, Articular, Male, Time Factors, Physiology, Articular cartilage, medicine.disease_cause, Tarsal Joints, Biochemistry, Jumping, Ankle Injuries, General Pharmacology, Toxicology and Pharmaceutics, lcsh:QH301-705.5, Early Ambulation, lcsh:R5-920, General Neuroscience, General Medicine, Synovial membrane, medicine.anatomical_structure, Anesthesia, lcsh:Medicine (General), Morphology, musculoskeletal diseases, medicine.medical_specialty, Immunology, Biophysics, Ocean Engineering, Immobilization, Chondrocytes, Weight Loss, Synovial joint, medicine, Animals, Tibia, Rats, Wistar, Joint (geology), Swimming, business.industry, Body Weight, Biomedical Sciences, Remobilization in aquatic environment, Cell Biology, medicine.disease, Surgery, lcsh:Biology (General), Sprained ankle, Sprains and Strains, Ankle, business |
| الوصف: | A sprained ankle is a common musculoskeletal sports injury and it is often treated by immobilization of the joint. Despite the beneficial effects of this therapeutic measure, the high prevalence of residual symptoms affects the quality of life, and remobilization of the joint can reverse this situation. The aim of this study was to analyze the effects of immobilization and remobilization on the ankle joint of Wistar rats. Eighteen male rats had their right hindlimb immobilized for 15 days, and were divided into the following groups: G1, immobilized; G2, remobilized freely for 14 days; and G3, remobilized by swimming and jumping in water for 14 days, performed on alternate days, with progression of time and a series of exercises. The contralateral limb was the control. After the experimental period, the ankle joints were processed for microscopic analysis. Histomorphometry did not show any significant differences between the control and immobilized/remobilized groups and members, in terms of number of chondrocytes and thickness of the articular cartilage of the tibia and talus. Morphological analysis of animals from G1 showed significant degenerative lesions in the talus, such as exposure of the subchondral bone, flocculation, and cracks between the anterior and mid-regions of the articular cartilage and the synovial membrane. Remobilization by therapeutic exercise in water led to recovery in the articular cartilage and synovial membrane of the ankle joint when compared with free remobilization, and it was shown to be an effective therapeutic measure in the recovery of the ankle joint. |
| وصف الملف: | text/html |
| تدمد: | 1414-431X 0100-879X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1da1446e3b4e7ec1f05b5747f6a6e9Test https://doi.org/10.1590/1414-431x20143795Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bc1da1446e3b4e7ec1f05b5747f6a6e9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1414431X 0100879X |
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