Efeito da dexmedetomidina em crianças submetidas à anestesia geral com sevoflurano
| العنوان: | Efeito da dexmedetomidina em crianças submetidas à anestesia geral com sevoflurano |
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| المؤلفون: | Denismar Borges de Miranda, Luís Cláudio de Araújo Ladeira, Marco Aurélio Soares Amorim, Larissa Govêia Moreira, Cátia Sousa Govêia, Edno Magalhães |
| المصدر: | Revista Brasileira de Anestesiologia v.67 n.2 2017 Revista Brasileira de Anestesiologia Sociedade Brasileira de Anestesiologia (SBA) instacron:SBA Repositório Institucional da UnB Universidade de Brasília (UnB) instacron:UNB Brazilian Journal of Anesthesiology, Vol 67, Iss 2, Pp 193-198 (2017) Revista Brasileira de Anestesiologia, Volume: 67, Issue: 2, Pages: 193-198, Published: APR 2017 Revista Brasileira de Anestesiologia, Vol 67, Iss 2, Pp 193-198 |
| بيانات النشر: | Elsevier BV, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Methyl Ethers, Psychomotor agitation, Nausea, General anesthesia, Anesthesia, General, Placebo, Anestesia geral, Sevoflurane, Pacu, lcsh:RD78.3-87.3, Metanálise, 03 medical and health sciences, Inhalational anesthetics, 0302 clinical medicine, Double-Blind Method, 030202 anesthesiology, medicine, Humans, Hypnotics and Sedatives, 030212 general & internal medicine, Dexmedetomidine, Child, Anestésicos inalatórios, Psychomotor Agitation, Randomized Controlled Trials as Topic, biology, business.industry, General Medicine, biology.organism_classification, Meta-analysis, Dexmedetomidina, lcsh:Anesthesiology, Anesthesia, Anesthetics, Inhalation, Postoperative Nausea and Vomiting, Premedication, medicine.symptom, business, Pediatric anesthesia, Agitação psicomotora, medicine.drug |
| الوصف: | Background and objectives: Sevoflurane is often used in pediatric anesthesia and is associated with high incidence of psychomotor agitation. In such cases, dexmedetomidine (DEX) has been used, but its benefit and implications remain uncertain. We assessed the effects of DEX on agitation in children undergoing general anesthesia with sevoflurane. Method: Meta-analysis of randomized clinical and double-blind studies, with children undergoing elective procedures under general anesthesia with sevoflurane, using DEX or placebo. We sought articles in English in PubMed database using the following terms: Dexmedetomidine, sevoflurane (Methyl Ethers/sevoflurante), and agitation (Psychomotor Agitation). Duplicate articles with children who received premedication and used active control were excluded. It was adopted random effects model with DerSimonian–Laird testing and odds ratio (OR) calculation for dichotomous variables, and standardized mean difference for continuous variables, with their respective 95% confidence interval (CI). Results: Of 146 studies identified, 10 were selected totaling 558 patients (282 in DEX group and 276 controls). The use of DEX was considered a protective factor for psychomotor agitation (OR = 0.17; 95% CI 0.13–0.23; p |
| وصف الملف: | text/html |
| تدمد: | 0104-0014 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9019ce2dbba7c18b975055640ededf77Test https://doi.org/10.1016/j.bjane.2016.02.007Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9019ce2dbba7c18b975055640ededf77 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01040014 |
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