Differences in Cortical Sources of the Event-Related P3 Potential Between Young and Old Participants Indicate Frontal Compensation
| العنوان: | Differences in Cortical Sources of the Event-Related P3 Potential Between Young and Old Participants Indicate Frontal Compensation |
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| المؤلفون: | van Dinteren, R., Huster, R. J., Jongsma, M. L.A., Kessels, R. P.C., Arns, M., Afd Psychologische functieleer, Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF) |
| المساهمون: | Afd Psychologische functieleer, Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF) |
| المصدر: | Brain Topography, 31(1), 35. Kluwer Academic/Human Sciences Press Inc. Brain Topography, 31, 1, pp. 35-46 Brain Topography, 31, 35-46 Brain Topography, 31(1), 35-46. Springer, Cham Brain Topography |
| بيانات النشر: | Springer Nature |
| مصطلحات موضوعية: | Male, Aging, Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1], Neurology, INDEPENDENT COMPONENTS, Electroencephalography, Audiology, Developmental psychology, Cognition, 0302 clinical medicine, EEG, P300, BRAIN, Event (probability theory), Aged, 80 and over, Principal Component Analysis, medicine.diagnostic_test, Radiological and Ultrasound Technology, 05 social sciences, P3, Middle Aged, Magnetic Resonance Imaging, Frontal Lobe, medicine.anatomical_structure, N-BACK TASK, Radiology Nuclear Medicine and imaging, Female, Anatomy, Psychology, Parahippocampal gyrus, ERP, Adult, medicine.medical_specialty, Adolescent, Clinical Neurology, Learning and Plasticity, 050105 experimental psychology, Young Adult, 03 medical and health sciences, WORKING-MEMORY, AGE, Cognitive change, Reaction Time, medicine, Humans, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, SOURCE LOCALIZATION, Aged, Original Paper, ELECTROMAGNETIC TOMOGRAPHY, Neuro- en revalidatiepsychologie, LATE ERP RESPONSES, Neuropsychology and rehabilitation psychology, Precentral gyrus, Plasticity and Memory [DI-BCB_DCC_Theme 3], DEVIANT STIMULI, Event-Related Potentials, P300, Scalp, Neurology (clinical), Psychomotor Performance, 030217 neurology & neurosurgery |
| الوصف: | Contains fulltext : 181771.pdf (Publisher’s version ) (Open Access) The event-related P3 potential, as elicited in auditory signal detection tasks, originates from neural activity of multiple cortical structures and presumably reflects an overlap of several cognitive processes. The fact that the P3 is affected by aging makes it a potential metric for age-related cognitive change. The P3 in older participants is thought to encompass frontal compensatory activity in addition to task-related processes. The current study investigates this by decomposing the P3 using group independent component analysis (ICA). Independent components (IC) of young and old participants were compared in order to investigate the effects of aging. Exact low-resolution tomography analysis (eLORETA) was used to compare current source densities between young and old participants for the P3-ICs to localize differences in cortical source activity for every IC. One of the P3-related ICs reflected a different constellation of cortical generators in older participants compared to younger participants, suggesting that this P3-IC reflects shifts in neural activations and compensatory processes with aging. This P3-IC was localized to the orbitofrontal/temporal, and the medio-parietal regions. For this IC, older participants showed more frontal activation and less parietal activation as measured on the scalp. The differences in cortical sources were localized in the precentral gyrus and the parahippocampal gyrus. This finding might reflect compensatory activity recruited from these cortical sources during a signal detection task. 12 p. |
| وصف الملف: | image/pdf; application/pdf |
| اللغة: | English |
| تدمد: | 0896-0267 |
| DOI: | 10.1007/s10548-016-0542-y |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d2ede02a30878dc57c81e9703a2233Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d1d2ede02a30878dc57c81e9703a2233 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 08960267 |
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| DOI: | 10.1007/s10548-016-0542-y |