Troublesome heterotopic ossification and stroke: Features and risk factors. A case control study

التفاصيل البيبلوغرافية
العنوان: Troublesome heterotopic ossification and stroke: Features and risk factors. A case control study
المؤلفون: Alexis Ruet, François Genêt, Claire Jourdan, Alexis Schnitzler, Kambiz Minooee, Philippe Denormandie
المصدر: Brain Injury. 29:866-871
بيانات النشر: Informa UK Limited, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Male, medicine.medical_specialty, Pediatrics, Time Factors, Neuroscience (miscellaneous), Risk Factors, Epidemiology, Ischaemic stroke, Developmental and Educational Psychology, medicine, Retrospective analysis, Humans, cardiovascular diseases, Risk factor, Stroke, Aged, Retrospective Studies, business.industry, Ossification, Heterotopic, Case-control study, Mean age, Middle Aged, medicine.disease, Surgery, Logistic Models, Case-Control Studies, Female, Heterotopic ossification, Neurology (clinical), business
الوصف: To determine the features of stroke-related HO in a large sample of patients and to assess if HO risk is increased by haemorrhagic stroke.A case control study (risk factor of a rare event using retrospective analysis).Sixty-one patients with stroke-81 troublesome HOs-were included, each was matched with four controls, i.e. 244 patients with no HO after stroke. Matching criteria were age (±3.5 years) and sex. Data recorded were time from stroke to surgery, ischaemic or haemorrhagic stroke and presence of HO risk factors.Mean age at time of stroke = 46.02 ± 11.4 years (15.9-76.3) for the case sub-group. Time from stroke to surgery = 23.4 ± 27.8 months (3.6-150.0). There was a significant relationship between haemorrhagic stroke and HO development (OR = 3.01; 95% CI = 1.14-7.98; p 0.05), but not for ischaemic stroke. This became non-significant when all matching and risk factors were included in the model (adjusted OR = 1.98; 95% CI = 0.60-6.54; p = 0.26).Haemorrhagic stroke appears to increase the risk of HO development. Further studies are required to determine if this risk factor is independent from other comorbid factors.
تدمد: 1362-301X
0269-9052
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9805ab8bed9d6fb2e18ecbd3d19f98Test
https://doi.org/10.3109/02699052.2015.1005133Test
رقم الانضمام: edsair.doi.dedup.....bf9805ab8bed9d6fb2e18ecbd3d19f98
قاعدة البيانات: OpenAIRE