Primary hepatic large B-cell lymphoma following direct-acting antiviral treatment for hepatitis C
| العنوان: | Primary hepatic large B-cell lymphoma following direct-acting antiviral treatment for hepatitis C |
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| المؤلفون: | Myriam Jrad, Y Zaimi, S Ayadi, Feryel Letaief Ksontini, Emna Bel Hadj Mabrouk, Walid Cherifi, M Ayari |
| المصدر: | BMJ Open Gastroenterology, Vol 8, Iss 1 (2021) BMJ Open Gastroenterology |
| بيانات النشر: | BMJ Publishing Group, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Cirrhosis, Hepatitis C virus, Lymphoproliferative disorders, lymphoma, Hepacivirus, RC799-869, medicine.disease_cause, Antiviral Agents, Gastroenterology, Liver disease, Internal medicine, antiviral therapy, medicine, Humans, B-cell lymphoma, Hepatology, business.industry, cirrhosis, Liver Neoplasms, Hepatitis C, Hepatitis C, Chronic, Diseases of the digestive system. Gastroenterology, medicine.disease, Transplantation, Hepatocellular carcinoma, HCV, Lymphoma, Large B-Cell, Diffuse, business |
| الوصف: | Hepatitis C virus (HCV) infection is a major public health concern worldwide, raising important medical and economic issues. HCV-related end-stage liver disease is one of the most common indications for hepatic transplantation. Chronic hepatitis C is also assimilated to a systemic disease because of multiple extrahepatic manifestations, including lymphoproliferative disorders. The revolution of HCV treatment with the advent of direct-acting antivirals has significantly improved the management with high antiviral efficacy and good safety profile compared with old regimens, thus allowing good outcomes on hepatic and extrahepatic symptoms. However, with the widespread use of these new agents, controversial concerns about unexpected increasing cases of hepatocellular carcinoma were reported. We now report the case of a patient presenting with HCV-related cirrhosis, treated with direct-antiviral therapy and diagnosed with primary hepatic lymphoma shortly after the end of the treatment. |
| اللغة: | English |
| تدمد: | 2054-4774 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c40752b7b689e1a09fb11138ab115aTest https://bmjopengastro.bmj.com/content/8/1/e000721.fullTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....01c40752b7b689e1a09fb11138ab115a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20544774 |
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