Education achievement and type 2 diabetes—what mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study
| العنوان: | Education achievement and type 2 diabetes—what mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study |
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| المؤلفون: | Steele, Christopher, Schottker, Ben, Marshall, Adele M, Kouvonen, Anne Maria, O'Doherty, Mark G, Mons, U, Saum, K U, Boffetta, P, Trichopoulou , A, Brenner, Herman, Kee, Frank |
| المساهمون: | Steele, C.J. and Schöttker, B. and Marshall, A.H. and Kouvonen, A. and O'Doherty, M.G. and Mons, U. and Saum, K.-U. and Boffetta, P. and Trichopoulou, A. and Brenner, H. and Kee, F., Department of Social Research (2010-2017), Social Policy, Center for Population, Health and Society |
| المصدر: | BMJ Open Steele, C J, Schöttker, B, Marshall, A H, Kouvonen, A, O'Doherty, M G, Mons, U, Saum, K-U, Boffetta, P, Trichopoulou, A, Brenner, H & Kee, F 2017, ' Education achievement and type 2 diabetes-what mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study ', BMJ Open, vol. 7, no. 4, e013569 . https://doi.org/10.1136/bmjopen-2016-013569Test |
| بيانات النشر: | BMJ Open, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, obesity, food intake, endocrine system diseases, proportional hazards model, groups by age, cholesterol blood level, physical activity, Triglyceride, Body Mass Index, older adult, Cohort Studies, underweight, high density lipoprotein cholesterol, Germany, vegetable, social class, Aged, hemoglobin A1c, triacylglycerol, academic achievement, older adults, family history, C reactive protein, adult, Incidence, Smoking, drinking behavior, socioeconomic position, Middle Aged, 3142 Public health care science, environmental and occupational health, educational statu, Social Cla, Diabetes and Endocrinology, 5142 Social policy, 5141 Sociology, Hypertension, Educational Status, Female, triacylglycerol, diet restriction, Human, Alcohol Drinking, non insulin dependent diabetes mellitu, alcohol consumption, education, cohort analysi, Article, multivitamin, SDG 3 - Good Health and Well-being, blood, Type 2 diabetes mellitus, Journal Article, follow up, Humans, mediation, Exercise, Triglycerides, Aged, Dyslipidemias, Proportional Hazards Models, hemoglobin blood level, Research, dyslipidemia, Cholesterol, HDL, nutritional and metabolic diseases, vitamin supplementation, fruit, triacylglycerol blood level, major clinical study, Diabetes Mellitus, Type 2, Social Class, Cohort Studie, population research, body ma |
| الوصف: | Objective: The study aims to identify the mediating factors of the relationship between education achievement and incident type 2 diabetes mellitus (T2DM) in older adults. Design: Population-based cohort study. Setting Participants were recruited from the German federal state of Saarland. Participants: Participants were excluded if they had prevalent T2DM or missing data on prevalent T2DM, missing or zero follow-up time for incident T2DM or were under 50 years of age. The total sample consisted of 7462 individuals aged 50-75 years (42.8% men, mean age 61.7 years) at baseline (2000-02). The median follow-up time was 8.0 years. Methods: Cox proportional hazards regression was initially used to determine the direct association between education achievement and incident T2DM. Using the Baron and Kenny approach, we then investigated the associations between education achievement and incident T2DM with the potential mediators. The contribution of each of the putative mediating variables was then calculated. Results: A clear socioeconomic gradient was observed with regard to T2DM incidence with the lowest educated individuals at a greater risk of developing the disease during the follow-up period: HR (95% CI) high education: 0.52 (0.34 to 0.80); medium education: 0.80 (0.66 to 0.96). Seven of the variables considered explained a proportion of the education-T2DM relationship (body mass index, alcohol consumption, hypertension, fasting triglycerides, high-density lipoprotein (HDL) cholesterol, physical activity and smoking status), where the contribution of the variables ranged from 1.0% to 17.7%. Overall, the mediators explained 31.7% of the relationship. Conclusion: By identifying the possible mediating factors of the relationship between education achievement and incident T2DM in older adults, the results of this study can be used to assist with the development of public health strategies that aim to reduce socioeconomic inequalities in T2DM. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. |
| وصف الملف: | application/pdf; ELETTRONICO |
| اللغة: | English |
| تدمد: | 2044-6055 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eaf5cd748681401bf78dffaf267f97b1Test http://europepmc.org/articles/PMC5719655Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....eaf5cd748681401bf78dffaf267f97b1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20446055 |
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