Comparative proteomic analysis reveals drug resistance of Staphylococcus xylosus ATCC700404 under tylosin stress
| العنوان: | Comparative proteomic analysis reveals drug resistance of Staphylococcus xylosus ATCC700404 under tylosin stress |
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| المؤلفون: | Wen-Qiang Cui, Xin Liu, Ruixiang Che, Jinpeng Wang, Mo Chen, Yanhua Li, Yong-Hui Zhou, Xing Xiaoxu, Fei Yu, Bello-Onaghise God'spower, Wen-Ya Ding |
| المصدر: | BMC Veterinary Research, Vol 15, Iss 1, Pp 1-11 (2019) BMC Veterinary Research |
| بيانات النشر: | BMC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Proteomics, Ribosomal Proteins, Proteome, 040301 veterinary sciences, Staphylococcus, animal diseases, Quantitative proteomics, Aldehyde dehydrogenase a, Drug resistance, Microbial Sensitivity Tests, Tylosin, Microbiology, 0403 veterinary science, 03 medical and health sciences, chemistry.chemical_compound, Thioredoxins, fluids and secretions, Bacterial Proteins, Ribosomal protein, Drug Resistance, Bacterial, Thioredoxin, Pathogen, 030304 developmental biology, Drug-resistance, 0303 health sciences, lcsh:Veterinary medicine, General Veterinary, biology, Staphylococcus xylosus, 04 agricultural and veterinary sciences, General Medicine, Gene Expression Regulation, Bacterial, Ribosomal protein L23, Aldehyde Dehydrogenase, biology.organism_classification, Anti-Bacterial Agents, chemistry, iTRAQ, lcsh:SF600-1100, Isobaric tag for relative and absolute quantitation, Research Article |
| الوصف: | Background As a kind of opportunist pathogen, Staphylococcus xylosus (S. xylosus) can cause mastitis. Antibiotics are widely used for treating infected animals and tylosin is a member of such group. Thus, the continuous use of antibiotics in dairy livestock enterprise will go a long way in increasing tylosin resistance. However, the mechanism of tylosin-resistant S. xylosus is not clear. Here, isobaric tag for relative and absolute quantitation (iTRAQ)-based quantitative proteomics methods was used to find resistance-related proteins. Results We compared the differential expression of S. xylosus in response to tylosin stress by iTRAQ. A total of 155 proteins (59 up-regulated, 96 down-regulated) with the fold-change of >1.2 or |
| اللغة: | English |
| تدمد: | 1746-6148 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9640ed5672b7a655a8f0b6eb03d249a2Test http://link.springer.com/article/10.1186/s12917-019-1959-9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9640ed5672b7a655a8f0b6eb03d249a2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17466148 |
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