Prevalence of pregnancy-relevant infections in a rural setting of Ghana
| العنوان: | Prevalence of pregnancy-relevant infections in a rural setting of Ghana |
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| المؤلفون: | Oliver Bader, Raimond Lugert, Fabian M. Völker, A. Uy, Ortrud Zimmermann, Paul Cooper, Uwe Groß |
| المصدر: | BMC Pregnancy and Childbirth, Vol 17, Iss 1, Pp 1-7 (2017) BMC Pregnancy and Childbirth |
| بيانات النشر: | BMC, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Rural Population, Herpesvirus 3, Human, Prevalence, Cytomegalovirus, Pilot Projects, Ghana, 0302 clinical medicine, Risk Factors, Seroepidemiologic Studies, Pregnancy, Parvovirus B19, Human, 030212 general & internal medicine, Pregnancy Complications, Infectious, Obstetrics, 1. No poverty, Obstetrics and Gynecology, Hepatitis C, Middle Aged, Hepatitis B, 3. Good health, Group B streptococci, Female, Toxoplasma, Research Article, Adult, medicine.medical_specialty, Adolescent, Listeria, 030231 tropical medicine, Infections, Rubella, lcsh:Gynecology and obstetrics, Young Adult, 03 medical and health sciences, Streptococcal Infections, medicine, Humans, Treponema pallidum, lcsh:RG1-991, Hepatitis, business.industry, medicine.disease, Brucella, Neisseria gonorrhoeae, Malaria, Cross-Sectional Studies, Immunoglobulin G, Immunology, Syphilis, business, Rubella virus |
| الوصف: | Background Although infectious diseases still account for a high burden of morbidity and mortality in sub-Saharan Africa, simultaneous investigations on multiple infections affecting maternal and child health are missing. Methods We conducted a cross-sectional, single-centre pilot study in a rural area of Ghana to assess the infectiological profile during pregnancy. Screening of 180 expectant mothers was done by vaginal swabs and serology to detect the most common pregnancy-relevant infections. They were also interviewed for potential risk factors, outcome of previous pregnancies, and socio-economic aspects. Results We found a high prevalence of infections caused by hepatitis B virus (16.7% HBs antigen positive). In contrast, infections caused by hepatitis C virus (1.1% anti-HCV) and HIV (0.6%) were rare. Maternal malaria was frequent (10.6%), despite increasing acceptance of intermittent preventive treatment during pregnancy (IPTp). Group B streptococci were present in 10.6% of all pregnant women. Absence of antibodies against varicella zoster virus in 43.2%, Toxoplasma gondii in 26.8%, parvovirus B19 in 20.0%, and rubella virus in 15.7% makes a significant proportion of pregnant women susceptible for acquiring primary infections. Whereas all study participants had specific IgG antibodies against human cytomegalovirus, infections with Listeria, Brucella, or Neisseria gonorrhoeae as well as active syphilis were absent. Conclusions Our pilot study in a rural community in Ghana indicates an urgent need for action in dealing at least with high-prevalent pregnancy-relevant infections, such as hepatitis B, malaria and those caused by group B streptococci. In addition, the resulting prevalence rates of various other infections may offer guidance for health officials to prioritize possible future intervention schemes. Electronic supplementary material The online version of this article (doi:10.1186/s12884-017-1351-3) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 1471-2393 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5897de59c9d719285c1914c796d4bbaTest http://link.springer.com/article/10.1186/s12884-017-1351-3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c5897de59c9d719285c1914c796d4bba |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712393 |
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