Randomised Controlled Trial to determine the appropriate time to initiate peritoneal dialysis after insertion of catheter to minimise complications (Timely PD study)
| العنوان: | Randomised Controlled Trial to determine the appropriate time to initiate peritoneal dialysis after insertion of catheter to minimise complications (Timely PD study) |
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| المؤلفون: | Helen Healy, Melanie Watson, Thin Han, Nicola Williams, Robert G. Fassett, Dwarakanathan Ranganathan, Richard Baer |
| المصدر: | BMC Nephrology, Vol 11, Iss 1, p 11 (2010) BMC Nephrology |
| بيانات النشر: | BMC, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Male, Tenckhoff catheter, Nephrology, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Peritonitis, lcsh:RC870-923, Catheterization, law.invention, Peritoneal dialysis, Catheters, Indwelling, Peritoneal Dialysis, Continuous Ambulatory, Randomized controlled trial, law, Internal medicine, Study protocol, medicine, Humans, Single-Blind Method, Dialysis, Catheter insertion, business.industry, Data Collection, Patient Selection, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, Surgery, Catheter, Research Design, Kidney Failure, Chronic, Female, Queensland, business, Peritoneal Dialysis |
| الوصف: | Background The most appropriate time to initiate dialysis after surgical insertion of Tenckhoff catheters is not clear in the literature. There is the possibility of peritoneal dialysis (PD) complications such as leakage and infection if dialysis is started too soon after insertion. However, much morbidity and expense could be saved by reducing dependency on haemodialysis (HD) by earlier initiation of PD post catheter insertion. Previous studies are observational and mostly compare immediate with delayed use. The primary objective is to determine the safest and shortest time interval between surgical placement of a Tenckhoff catheter and starting PD. Methods/Design This is a randomised controlled trial of patients who will start PD after insertion of Tenckhoff catheter at Royal Brisbane and Women's Hospital (RBWH) or Rockhampton Base Hospital (RBH) who meet the inclusion criteria. Patients will be stratified by site and diabetic status. The patients will be randomised to one of three treatment groups. Group 1 will start PD one week after Tenckhoff catheter insertion, group 2 at two weeks and group 3 at four weeks. Nurses and physicians will be blinded to the randomised allocation. The primary end point is the complication rate (leaks and infection) after initiation of PD. Discussion The study will determine the most appropriate time to initiate PD after placement of a Tenckhoff catheter. Trial Registration ACTRN12610000076077 |
| اللغة: | English |
| تدمد: | 1471-2369 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31be318e93093731785a883a63dd4ebTest http://www.biomedcentral.com/1471-2369/11/11Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f31be318e93093731785a883a63dd4eb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712369 |
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