Evaluating the profound effect of gut microbiome on host appetite in pigs
| العنوان: | Evaluating the profound effect of gut microbiome on host appetite in pigs |
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| المؤلفون: | Congying Chen, Lusheng Huang, Shanlin Ke, Jun Gao, Jinyuan Wu, Ming Yang, Hui Yang, Hao Fu, Shaoming Fang, Yunyan Zhou, Xiaochang Huang, Maozhang He |
| المصدر: | BMC Microbiology, Vol 18, Iss 1, Pp 1-10 (2018) BMC Microbiology |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Microbiology (medical), Feed intake, Swine, media_common.quotation_subject, 030106 microbiology, lcsh:QR1-502, Appetite, Gut microbiota, Gut flora, Microbiology, lcsh:Microbiology, 03 medical and health sciences, Function prediction, Lactobacillus, Prevotella, Animals, Food science, 16S rRNA, Enterotype, Phylogeny, media_common, Pig, Bacteria, biology, Host (biology), Feeding Behavior, Fatty Acids, Volatile, biology.organism_classification, Gastrointestinal Microbiome, 030104 developmental biology, Female, Research Article, Ruminococcaceae |
| الوصف: | Background There are growing evidences showing that gut microbiota should play an important role in host appetite and feeding behavior. However, what kind of microbe(s) and how they affect porcine appetite remain unknown. Results In this study, 280 commercial Duroc pigs were raised in a testing station with the circadian feeding behavior records for a continuous period of 30–100 kg. We first analyzed the influences of host gender and genetics in porcine average daily feed intake (ADFI), but no significant effect was observed. We found that the Prevotella-predominant enterotype had a higher ADFI than the Treponema enterotype-like group. Furthermore, 12 out of the 18 OTUs positively associated with the ADFI were annotated to Prevotella, and Prevotella was the hub bacteria in the co-abundance network. These results suggested that Prevotella might be a keystone bacterial taxon for increasing host feed intake. However, some bacteria producing short-chain fatty acids (SCFAs) and lactic acid (e.g. Ruminococcaceae and Lactobacillus) showed negative associations with the ADFI. Predicted function capacity analysis showed that the genes for amino acid biosynthesis had significantly different enrichment between pigs with high and low ADFI. Conclusions The present study provided important information on the profound effect of gut microbiota on porcine appetite and feeding behavior. This will profit us to regulate porcine appetite through modulating the gut microbiome in the pig industry. Electronic supplementary material The online version of this article (10.1186/s12866-018-1364-8) contains supplementary material, which is available to authorized users. |
| اللغة: | English |
| تدمد: | 1471-2180 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a182759bde24938fcbcca9cfa3d78c1bTest http://link.springer.com/article/10.1186/s12866-018-1364-8Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a182759bde24938fcbcca9cfa3d78c1b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14712180 |
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