دورية أكاديمية

High frequency of alpha7-HPV in Colombian Caribbean coast women: cervical cancer screening analysis

التفاصيل البيبلوغرافية
العنوان: High frequency of alpha7-HPV in Colombian Caribbean coast women: cervical cancer screening analysis
المؤلفون: Heiser Arteaga-Pautt, O. Elias Bru-Cordero, Dina Ricardo-Caldera, Lyda Espitia-Pérez, Paula Avilés-Vergara, Catalina Tovar-Acero, Lorena Castaño-Caraballo, Sandra Janeth Perdomo-Lara, Helvey Ramón Zetién-Arteaga, Valentina Behaine-Bravo, Sara Cecilia Soto-De León
المصدر: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: High-risk human papillomavirus (HR-HPV), Cervical cancer (CC), Pap smear test, Population, Colombia, Infectious and parasitic diseases, RC109-216
الوصف: SUMMARY Background Cervical cancer (CC) is a significant global public health concern, particularly in developing countries such as Colombia. The main risk factor involves high-risk HPV types (HR-HPV) infection, coupled with population-specific variables. The Caribbean region in Colombia lacks research on HR-HPV-type frequencies. Therefore, this study aims to establish the prevalence of type-specific HR-HPV and its association with sociodemographic factors among women undergoing cervical cytology screening. Methods A cross-sectional study involving voluntary women who provided informed consent and completed a questionnaire capturing sociodemographic, clinical, and sexual behavior information was conducted. All participants underwent cervical cytology and molecular analysis. Generic HPV detection employed three simultaneous PCRs (GP5+/6+, MY09/11, and PU1R/2 M), and positive samples were genotyped using the Optiplex HPV Genotyping kit. The analysis encompassed the 12 types of high-risk HPV (HR-HPV-16,-18,-31,-33,-35,-39,-45,-51,-52,-56,-58, and − 59). Frequencies were reported based on geographic subregions within the Córdoba department, and disparities were made between single and multiple infections. Sociodemographic and clinical variables were subjected to ordinal logistic regression, with statistical significance at a p-value
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2334
العلاقة: https://doaj.org/toc/1471-2334Test
DOI: 10.1186/s12879-024-09410-0
الوصول الحر: https://doaj.org/article/2c88aa58a6794bc4baeb0b10f2e946c3Test
رقم الانضمام: edsdoj.2c88aa58a6794bc4baeb0b10f2e946c3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712334
DOI:10.1186/s12879-024-09410-0