دورية أكاديمية

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion caused by methicillin-sensitive Staphylococcus aureus bacteremia with toxic shock syndrome: a case report.

التفاصيل البيبلوغرافية
العنوان: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion caused by methicillin-sensitive Staphylococcus aureus bacteremia with toxic shock syndrome: a case report.
المؤلفون: Koki Kosami, Tsuneaki Kenzaka, Yuka Sagara, Kensuke Minami, Masami Matsumura, Kosami, Koki, Kenzaka, Tsuneaki, Sagara, Yuka, Minami, Kensuke, Matsumura, Masami
المصدر: BMC Infectious Diseases; 4/18/2016, Vol. 16, p1-5, 5p, 2 Color Photographs, 2 Charts, 1 Graph
مصطلحات موضوعية: TREATMENT of encephalitis, HEPATIC encephalopathy, PHYSIOLOGICAL effects of antibiotics, DRUG efficacy, LOGISTIC regression analysis
مستخلص: Background: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy caused by various pathological processes, but encephalopathy due to bacteria is rare. Case Presentation: We report the case of a 45-year-old Japanese woman who on receiving chemotherapy for advanced breast cancer developed an altered mental status and dysarthria soon after fever from infection of a subcutaneous implantable port. Staphylococcus aureus was detected in her blood cultures. Magnetic resonance imaging (MRI) revealed an ovoid lesion in the central portion of the splenium of the corpus callosum (SCC). Although hypotension was not observed, we diagnosed probable toxic shock syndrome (TSS) based on fever (temperature: >38.9 °C), altered mental status, erythema, desquamation, thrombocytopenia, liver dysfunction, and creatine phosphokinase elevation. We administered antimicrobial therapy and her neurological symptoms improved gradually. The lesion in the SCC completely disappeared on MRI 7 days after disease onset. Conclusions: We diagnosed this case as MERS caused by S. aureus bacteremia with TSS. This is the first report of such a case, and we suggest that when a TSS patient presents with neurological symptoms, the possibility of MERS should be considered. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:14712334
DOI:10.1186/s12879-016-1516-0