التفاصيل البيبلوغرافية
| العنوان: |
Prescription of potentially inappropriate medication in Korean older adults based on 2012 Beers Criteria: a cross-sectional population based study. |
| المؤلفون: |
You-Seon Nam, Jong Soo Han, Ju Young Kim, Woo Kyung Bae, Kiheon Lee, Nam, You-Seon, Han, Jong Soo, Kim, Ju Young, Bae, Woo Kyung, Lee, Kiheon |
| المصدر: |
BMC Geriatrics; 6/2/2016, Vol. 16, p1-9, 9p, 4 Charts |
| مصطلحات موضوعية: |
INAPPROPRIATE prescribing (Medicine), DISEASES in older people, KOREANS, COMORBIDITY, DISEASE prevalence, POLYPHARMACY, DISEASES, CROSS-sectional method, RETROSPECTIVE studies, PREVENTION |
| مصطلحات جغرافية: |
SOUTH Korea |
| مستخلص: |
Background: A high number of elderly people with multiple comorbidities are exposed to the risk of polypharmacy and prescription of potentially inappropriate medication (PIM). The purpose of this study was to determine the prevalence and patterns of PIM prescription in Korean older adults according to the 2012 Beers Criteria.Methods: A retrospective study was conducted using data from the Korean Health Insurance Review and Assessment (KHIRA) database of outpatient prescription claims collected from January 1, 2009 to December 31, 2011. A total of 523,811 elderly subjects aged 65 years and older were included in the study, and several covariates related to the prescription of PIMs were obtained from the KHIRA database. These covariates were analyzed using Student's t test and the chi-square test; furthermore, multivariate logistic regression analysis was used to evaluate the risk factors associated with the prescription of PIMs.Results: A total of 80.96 % subjects were prescribed at least one PIM independent of their diagnosis or condition according to the 2012 Beers Criteria. The most commonly prescribed medication class was first-generation antihistamines with anticholinergic properties (52.33 %). Pain medications (43.04 %) and benzodiazepines (42.53 %) were next in line. When considering subjects' diagnoses or conditions, subjects diagnosed with central nervous system conditions were most often prescribed PIMs. Female sex, severity of comorbidities, and polypharmacy were significant risk factors for PIM prescriptions.Conclusions: This study confirmed that PIM prescription is common among elderly Koreans. A clinical decision support system should be developed to decrease the prevalence of PIM prescriptions. [ABSTRACT FROM AUTHOR] |
|
Copyright of BMC Geriatrics is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder