دورية
A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia
| العنوان: | A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia |
|---|---|
| المؤلفون: | Masih, Katherine E., Gardner, Rebecca A., Chou, Hsien-Chao, Abdelmaksoud, Abdalla, Song, Young K., Mariani, Luca, Gangalapudi, Vineela, Gryder, Berkley E., Wilson, Ashley L., Adebola, Serifat O., Stanton, Benjamin Z., Wang, Chaoyu, Milewski, David, Kim, Yong Yean, Tian, Meijie, Tai-Chi Cheuk, Adam, Wen, Xinyu, Zhang, Yue, Altan-Bonnet, Grégoire, Kelly, Michael C., Wei, Jun S., Bulyk, Martha L., Jensen, Michael C., Orentas, Rimas J., Khan, Javed |
| المصدر: | Blood Advances; 20230101, Issue: Preprints |
| مستخلص: | •Multiomic investigation of pretreatment bone marrow identifies a primary nonresponder signature to CD19-CAR in childhood B-ALL.•Primary nonresponders harbor myeloid and stem-cell like features while maintaining a pre-B-cell phenotype. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 24739529 24739537 |
|---|---|
| DOI: | 10.1182/bloodadvances.2022008977 |