تقرير
Quality of life, psychological distress, and prognostic perceptions in caregivers of patients with multiple myeloma.
| العنوان: | Quality of life, psychological distress, and prognostic perceptions in caregivers of patients with multiple myeloma. |
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| المؤلفون: | O'Donnell, Elizabeth K, Shapiro, Yael N, Yee, Andrew J, Nadeem, Omar, Laubach, Jacob P, Branagan, Andrew R, Anderson, Kenneth C, Mo, Clifton C, Munshi, Nikhil C, Ghobrial, Irene M, Sperling, Adam S, Agyemang, Emerentia A, Burke, Jill N, Harrington, Cynthia C, Hu, Bonnie Y, Richardson, Paul G, Raje, Noopur S, El-Jawahri, Areej |
| المصدر: | Blood Adv ; ISSN:2473-9537 ; Volume:6 ; Issue:17 |
| بيانات النشر: | Silverchair Information Systems |
| سنة النشر: | 2022 |
| المجموعة: | PubMed Central (PMC) |
| الوصف: | Although caregivers of patients with multiple myeloma (MM) play a critical role in supporting their loved ones throughout the illness course, studies examining caregiver quality of life (QOL), psychological distress, and prognostic awareness are lacking. We conducted a cross-sectional, multisite study of patients undergoing treatment with MM and their caregivers. Eligible caregivers were enrolled to 1 of 3 cohorts based on lines of therapy. Caregivers completed validated questionnaires to assess their QOL, psychological distress, and perceptions of prognosis. We enrolled 127 caregivers of patients with MM (newly diagnosed [n = 43], 2-3 lines of therapy [n = 40], and ≥4 lines of therapy [n = 44]). Caregiver QOL and psychological distress did not differ by line of therapy. The rate of clinically significant anxiety, depression, and posttraumatic stress disorder symptoms were 44.1% (56/127), 15.8% (20/127), and 24.4% (31/127), respectively. When examined in dyads, caregivers reported higher rates of clinically significant anxiety (44.4% [55/124] vs 22.5% [28/124]) compared with patients with MM. Most caregivers (84.2%, 101/120) reported that the oncologist had informed them that the patient's cancer was incurable; however, only 50.9% (58/114) and 53.6% (59/110) of caregivers acknowledged the patient's cancer was terminal and incurable, respectively. Caregivers of patients undergoing treatment for MM experience substantial psychological distress across the disease continuum, particularly anxiety. The majority of caregivers of patients with MM report that knowing the patient's prognosis is extremely important and report that the oncologist told them that the patient was incurable. Nevertheless, a significant portion of caregivers believe that the patient's MM is curable. |
| نوع الوثيقة: | report article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1182/bloodadvances.2022007127Test; https://pubmed.ncbi.nlm.nih.gov/35848842Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631626Test/ |
| DOI: | 10.1182/bloodadvances.2022007127 |
| الإتاحة: | https://doi.org/10.1182/bloodadvances.2022007127Test https://pubmed.ncbi.nlm.nih.gov/35848842Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631626Test/ |
| حقوق: | © 2022 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved. |
| رقم الانضمام: | edsbas.C5B0BC92 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1182/bloodadvances.2022007127 |
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