نتائج البحث

1

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

المساهمون: Institut d'Histoire et de Philosophie des Sciences et des Techniques (IHPST), Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩

مصطلحات موضوعية: Adult, Male, MAPK/ERK pathway, CCR2, Myeloid, Cell Survival, MAP Kinase Signaling System, [SDV]Life Sciences [q-bio], Immunology, Chronic myelomonocytic leukemia, Biochemistry, Monocytes, 03 medical and health sciences, Chemokine receptor, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Humans, MCL1, Extracellular Signal-Regulated MAP Kinases, Autocrine signalling, Protein Kinase Inhibitors, Aged, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Kinase, Chemistry, [SHS.PHIL]Humanities and Social Sciences/Philosophy, Leukemia, Myelomonocytic, Chronic, Blood Proteins, Cell Biology, Hematology, Middle Aged, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a876fc49ce5e247d9cb91a3a300a22Test
https://doi.org/10.1182Test/blood.2020008729

2

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

المؤلفون: Satoshi Yamashita, Naoko Hattori, Yuki Kurahashi, Toshikazu Ushijima, Naoko Sueoka-Aragane, Tatsuro Watanabe, Akemi Sato, Kensuke Kojima, Hideaki Nakamura, Atsushi Kawaguchi, Shinya Kimura, Eisaburo Sueoka, Nao Yoshida, Kazuharu Kamachi, Seiji Okada, Hiroshi Ureshino, Yuki Fukuda-Kurahashi

المصدر: Blood. 136:871-884

مصطلحات موضوعية: Adult, 0301 basic medicine, Pyridines, viruses, Immunology, Administration, Oral, Decitabine, Antineoplastic Agents, Biology, Biochemistry, Mice, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, medicine, Animals, Humans, Leukemia-Lymphoma, Adult T-Cell, Molecular Targeted Therapy, Cells, Cultured, Aged, Mice, Knockout, Regulation of gene expression, Human T-lymphotropic virus 1, Mice, Inbred BALB C, Gene Expression Regulation, Leukemic, Cell growth, T-cell receptor, Drugs, Investigational, Cell Biology, Hematology, DNA Methylation, Cell Transformation, Viral, HTLV-I Infections, Xenograft Model Antitumor Assays, Demethylation, Demethylating agent, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Female, medicine.drug, DNA hypomethylation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0e7224c117c25f69a987a740a43e5Test
https://doi.org/10.1182Test/blood.2019003084

3

A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia

المصدر: Blood. 136:171-182

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2745a074f0e9fb3a40b7e799bc767c0Test
https://doi.org/10.1182Test/blood.2019004596

4

MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD

المصدر: Blood. 131:2846-2855

مصطلحات موضوعية: Adult, Oncology, medicine.medical_specialty, Multivariate analysis, Adolescent, medicine.medical_treatment, Immunology, Drug Resistance, Graft vs Host Disease, Pancreatitis-Associated Proteins, Biochemistry, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Adrenal Cortex Hormones, Internal medicine, medicine, Humans, Transplantation, Homologous, Child, Aged, Transplantation, Receiver operating characteristic, business.industry, Hematopoietic Stem Cell Transplantation, Area under the curve, Infant, Immunosuppression, Cell Biology, Hematology, Middle Aged, Prognosis, medicine.disease, Interleukin-1 Receptor-Like 1 Protein, Treatment Outcome, Graft-versus-host disease, Child, Preschool, 030220 oncology & carcinogenesis, Cohort, Biomarker (medicine), business, Biomarkers, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1e0e71c0b509f432cdd5374eab6952Test
https://doi.org/10.1182Test/blood-2018-01-822957

5

Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH

المؤلفون: Sharon Choo, Carrie Gifford, Rebecca A. Marsh, Adam Lane, Kejian Zhang, Tamar S. Rubin, Jack J. Bleesing

المصدر: Blood. 129:2993-2999

مصطلحات موضوعية: Pore Forming Cytotoxic Proteins, Adult, Male, 0301 basic medicine, Adolescent, Lymphocyte, DNA Mutational Analysis, Immunology, Biochemistry, Cell Degranulation, Lymphohistiocytosis, Hemophagocytic, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Lysosomal-Associated Membrane Protein 1, medicine, Humans, Cytotoxic T cell, UNC13D, Genetic Testing, Child, Immunobiology, Aged, Retrospective Studies, Genetic testing, biology, Receiver operating characteristic, medicine.diagnostic_test, Perforin, Infant, Newborn, Degranulation, Area under the curve, Infant, Cell Biology, Hematology, Middle Aged, Cytotoxicity Tests, Immunologic, Flow Cytometry, Killer Cells, Natural, Logistic Models, 030104 developmental biology, medicine.anatomical_structure, Child, Preschool, 030220 oncology & carcinogenesis, Mutation, biology.protein, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e4fc65784da709b936002e755b9df8Test
https://doi.org/10.1182Test/blood-2016-12-753830

6

Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma

المؤلفون: Catrina Fronick, Malachi Griffith, Matthew K. Matlock, Friederike Kreisel, Amanda F. Cashen, Lee Trani, Nancy L. Bartlett, Christopher A. Miller, Melissa M. Berrien-Elliott, Brian S. White, Todd A. Fehniger, Robert S. Fulton, Kilannin Krysiak, Felicia Gomez, Obi L. Griffith, Kenneth R. Carson

المصدر: Blood. 129:473-483

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Receptors, CXCR4, Vacuolar Proton-Translocating ATPases, Mutation rate, Immunology, Follicular lymphoma, Receptors, Antigen, B-Cell, Gene mutation, Biochemistry, Disease-Free Survival, Ion Channels, Histones, 03 medical and health sciences, 0302 clinical medicine, Agammaglobulinaemia Tyrosine Kinase, medicine, Humans, Bruton's tyrosine kinase, Lymphoma, Follicular, B cell receptor signaling pathway, Aged, Early Growth Response Protein 1, Aged, 80 and over, Receptors, Notch, biology, Gene Expression Profiling, breakpoint cluster region, Cell Biology, Hematology, Middle Aged, Protein-Tyrosine Kinases, medicine.disease, CREB-Binding Protein, Lymphoma, Gene Expression Regulation, Neoplastic, Repressor Proteins, Gene expression profiling, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Trans-Activators, biology.protein, Cancer research, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972759f35d0babd1032e41c9990f615fTest
https://doi.org/10.1182Test/blood-2016-07-729954

7

Anakinra as efficacious therapy for 2 cases of intracranial Erdheim-Chester disease

المؤلفون: Maria E. Arcila, Christian A. Bowers, Eli L. Diamond, Benjamin H. Durham, Lynn A. Brody, Omar Abdel-Wahab, Ahmet Dogan, Neval Ozkaya, Mark Fluchel

المصدر: Blood. 128:1896-1898

مصطلحات موضوعية: Central Nervous System, Male, 0301 basic medicine, Pathology, genetic structures, Drug Resistance, Letters to Blood, medicine.disease_cause, Biochemistry, 0302 clinical medicine, hemic and lymphatic diseases, MAP2K1, Medicine, Fatigue, Aged, 80 and over, Heart, Hematology, Middle Aged, C-Reactive Protein, Treatment Outcome, Organ Specificity, 030220 oncology & carcinogenesis, Disease Progression, Female, KRAS, medicine.drug, Adult, Erdheim-Chester Disease, medicine.medical_specialty, Immunology, Pain, Bone and Bones, Myeloid Neoplasm, Young Adult, 03 medical and health sciences, Humans, neoplasms, Aged, Anakinra, business.industry, Extramural, Myocardium, Interferon-alpha, Cell Biology, medicine.disease, Interleukin 1 Receptor Antagonist Protein, 030104 developmental biology, Positron-Emission Tomography, Erdheim–Chester disease, Cancer research, ARAF, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ca297d778ea70d8041c508849db153Test
https://doi.org/10.1182Test/blood-2016-06-725143

8

Phase 1 study of the PI3Kδ inhibitor INCB040093 ± JAK1 inhibitor itacitinib in relapsed/refractory B-cell lymphoma

المؤلفون: Moshe Talpaz, Tycel Phillips, Paul M. Barr, Peggy Scherle, Patrick B. Johnston, Li Zhou, Andres Forero-Torres, Taimur Sher, Catherine Diefenbach, Jennifer Pulini, Xuejun Chen

المصدر: Blood. 132(3)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Lymphoma, B-Cell, Combination therapy, Class I Phosphatidylinositol 3-Kinases, Immunology, Follicular lymphoma, Biochemistry, Gastroenterology, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, Young Adult, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, B-cell lymphoma, Adverse effect, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Lymphoid Neoplasia, Chlorambucil, business.industry, Cell Biology, Hematology, Janus Kinase 1, Middle Aged, medicine.disease, Combined Modality Therapy, Lymphoma, 030104 developmental biology, Treatment Outcome, Research Design, 030220 oncology & carcinogenesis, Pharmacodynamics, Female, business, Diffuse large B-cell lymphoma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaeaddd8a9603b09e33448057f91903Test
https://pubmed.ncbi.nlm.nih.gov/30026300Test

9

Checking up on checkpoint inhibitors

المؤلفون: Richard F. Little, Howard Streicher

المصدر: Blood. 130:107-108

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Transplantation Conditioning, DNA damage, Immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, Immunology, Gene Expression, Graft vs Host Disease, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Inside BLOOD Commentary, hemic and lymphatic diseases, Relapsed lymphoma, Humans, Transplantation, Homologous, Medicine, Checkpoint Kinase 2, Aged, Retrospective Studies, Salvage Therapy, Hematopoietic cell, business.industry, Remission Induction, Hematopoietic Stem Cell Transplantation, Antibodies, Monoclonal, Cell Biology, Hematology, Middle Aged, Hodgkin Disease, Survival Analysis, Blockade, Nivolumab, Treatment Outcome, surgical procedures, operative, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Female, Programmed death 1, Neoplasm Recurrence, Local, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67118d459b309518d1a8409567c83bb5Test
https://doi.org/10.1182Test/blood-2017-05-783696

10

Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

المؤلفون: Clare Gould, David Arpon, Frank Vari, Simone Birch, Mark Hertzberg, Maher K. Gandhi, Annette Hernandez, Dipti Talaulikar, Qingyan Cui, Erica Han, Colm Keane, Robert Bird, Josh Tobin, Sanjiv Jain, Donna Cross

المصدر: Blood. 131(16)

مصطلحات موضوعية: 0301 basic medicine, Male, Programmed Cell Death 1 Receptor, Biochemistry, B7-H1 Antigen, Monocytes, Antibodies, Monoclonal, Murine-Derived, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, education.field_of_study, biology, Chemistry, Hematology, Hodgkin Disease, Vinblastine, Neoplasm Proteins, Dacarbazine, Killer Cells, Natural, medicine.anatomical_structure, Vincristine, 030220 oncology & carcinogenesis, Female, Lymphoma, Large B-Cell, Diffuse, Rituximab, medicine.drug, Adult, Immunology, Population, 03 medical and health sciences, Bleomycin, Immune system, PD-L1, medicine, Humans, education, Cyclophosphamide, B cell, Macrophages, Models, Immunological, Cell Biology, medicine.disease, Lymphoma, 030104 developmental biology, Doxorubicin, biology.protein, Cancer research, Prednisone, Tumor Escape, Lymph Nodes, CD163, Diffuse large B-cell lymphoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174596090a8a42d0390c2b7511e879d7Test
https://pubmed.ncbi.nlm.nih.gov/29674350Test

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