Differences between unipolar mania and bipolar-I disorder: Evidence from nine epidemiological studies
| العنوان: | Differences between unipolar mania and bipolar-I disorder: Evidence from nine epidemiological studies |
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| المؤلفون: | Rosalind Lieb, Hans-Ulrich Wittchen, Mehdi Gholam-Rezaee, Wulf Rössler, Karen Jansen, Caroline L. Vandeleur, Kathleen R. Merikangas, Femke Lamers, Ricardo Azevedo da Silva, Brenda W.J.H. Penninx, Christoffel Grobler, Taiane de Azevedo Cardoso, Vladeta Ajdacic-Gross, Laura Helena Andrade, Luciano Dias de Mattos Souza, Maria Carmen Viana, Lihong Cui, Jules Angst, Flávio Kapczinski, Eva Asselmann, Katja Beesdo-Baum, Felix Angst, Martin Preisig |
| المساهمون: | Psychiatry, APH - Mental Health, APH - Digital Health |
| المصدر: | Angst, J, Rössler, W, Ajdacic-Gross, V, Angst, F, Wittchen, H U, Lieb, R, Beesdo-Baum, K, Asselmann, E, Merikangas, K R, Cui, L, Andrade, L H, Viana, M C, Lamers, F, Penninx, B W JH, de Azevedo Cardoso, T, Jansen, K, Dias de Mattos Souza, L, Azevedo da Silva, R, Kapczinski, F, Grobler, C, Gholam-Rezaee, M, Preisig, M & Vandeleur, C L 2019, ' Differences between unipolar mania and bipolar-I disorder : Evidence from nine epidemiological studies ', Bipolar Disorders, vol. 21, no. 5, pp. 437-448 . https://doi.org/10.1111/bdi.12732Test Bipolar disorders, vol. 21, no. 5, pp. 437-448 Bipolar Disorders, 21(5), 437-448. Blackwell Munksgaard |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Bipolar I disorder, Bipolar Disorder, Adolescent, Substance-Related Disorders, Population, Suicide, Attempted, Comorbidity, Anxiety, behavioral disciplines and activities, 03 medical and health sciences, Young Adult, 0302 clinical medicine, mental disorders, Prevalence, Medicine, Humans, Family history, Age of Onset, education, Psychiatry, Temperament, Biological Psychiatry, education.field_of_study, Depressive Disorder, Binge eating, business.industry, Panic, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Anxiety/epidemiology, Anxiety/psychology, Bipolar Disorder/epidemiology, Bipolar Disorder/psychology, Depressive Disorder/epidemiology, Depressive Disorder/psychology, Female, Suicide, Attempted/statistics & numerical data, bipolar-I disorder, comorbidity, epidemiology, family history, gender, mania, medicine.symptom, business, Mania, 030217 neurology & neurosurgery |
| الوصف: | Objectives Although clinical evidence suggests important differences between unipolar mania and bipolar-I disorder (BP-I), epidemiological data are limited. Combining data from nine population-based studies, we compared subjects with mania (M) or mania with mild depression (Md) to those with BP-I with both manic and depressive episodes with respect to demographic and clinical characteristics in order to highlight differences. Methods Participants were compared for gender, age, age at onset of mania, psychiatric comorbidity, temperament, and family history of mental disorders. Generalized linear mixed models with adjustment for sex and age as well as for each study source were applied. Analyses were performed for the pooled adult and adolescent samples, separately. Results Within the included cohorts, 109 adults and 195 adolescents were diagnosed with M/Md and 323 adults and 182 adolescents with BP-I. In both adult and adolescent samples, there was a male preponderance in M/Md, whereas lifetime generalized anxiety and/panic disorders and suicide attempts were less common in M/Md than in BP-I. Furthermore, adults with mania revealed bulimia/binge eating and drug use disorders less frequently than those with BP-I. Conclusions The significant differences found in gender and comorbidity between mania and BP-I suggest that unipolar mania, despite its low prevalence, should be established as a separate diagnosis both for clinical and research purposes. In clinical settings, the rarer occurrence of suicide attempts, anxiety, and drug use disorders among individuals with unipolar mania may facilitate successful treatment of the disorder and lead to a more favorable course than that of BP-I disorder. |
| وصف الملف: | application/pdf |
| تدمد: | 1399-5618 1398-5647 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f0f33af42f31664771684b32c961cdTest https://pubmed.ncbi.nlm.nih.gov/30475430Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....73f0f33af42f31664771684b32c961cd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13995618 13985647 |
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