Zirkuläre RNAs: neue Spieler im Kreise der Genregulation
| العنوان: | Zirkuläre RNAs: neue Spieler im Kreise der Genregulation |
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| المؤلفون: | Christian Bär, Laura Santer, Thomas Thum |
| المصدر: | BIOspektrum. 24:12-15 |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Whole Transcriptome Sequencing, Pharmacology toxicology, Computational biology, Biology, Molecular Biology, Gene, Biotechnology |
| الوصف: | High throughput whole transcriptome sequencing led to the discovery of a new class of non-coding RNAs: circular RNAs (circRNAs). Such single-stranded continuous loop RNAs exist for thousands of genes. Here, we present an overview of circRNA discovery and formation. We sum up some circRNA detection methods and highlight different molecular mechanisms of action. However, circRNA functional characterization is still at its very beginning and thus an increasing research field in our and other groups. |
| تدمد: | 1868-6249 0947-0867 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::768869e83e250d3d0519df17a03ee602Test https://doi.org/10.1007/s12268-018-0882-0Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........768869e83e250d3d0519df17a03ee602 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18686249 09470867 |
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