Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins

التفاصيل البيبلوغرافية
العنوان: Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins
المؤلفون: Hyung Kyu Lee, Nam-In Baek, Byoung-Mog Kwon, Dong Sung Kim, Jong Dae Park, Young-Kook Kim, Mi Kyung Kim, Shin Il Kim
المصدر: Bioorganicmedicinal chemistry letters. 9(10)
سنة النشر: 1999
مصطلحات موضوعية: Sapogenins, Clinical Biochemistry, Sterol O-acyltransferase, Saponin, Pharmaceutical Science, Panax, Sapogenin, complex mixtures, Biochemistry, chemistry.chemical_compound, Ginseng, Drug Discovery, Animals, Enzyme Inhibitors, Molecular Biology, Protopanaxatriol, chemistry.chemical_classification, Plants, Medicinal, Traditional medicine, biology, Anticholesteremic Agents, Organic Chemistry, Panaxatriol, food and beverages, Saponins, biology.organism_classification, Rats, chemistry, Microsomes, Liver, Molecular Medicine, Protopanaxadiol, Araliaceae, lipids (amino acids, peptides, and proteins), Sterol O-Acyltransferase
الوصف: Ginseng sapogenins were produced from ginseng saponins, isolated from Korean ginseng roots. Ginseng saponins very mildly inhibited acyl-CoA:cholesterol acyltransferase (ACAT) in vitro, however, the sapogenins showed strong inhibitory activity on microsomal ACAT. Therefore, the sapogenins will be one of key ingredients of ginseng affected a lowering of the serum total cholesterol level.
تدمد: 0960-894X
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c905fd738ccd45bfe31ddf3c5ad8f924Test
https://pubmed.ncbi.nlm.nih.gov/10360739Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....c905fd738ccd45bfe31ddf3c5ad8f924
قاعدة البيانات: OpenAIRE