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1
المؤلفون: Mónica Valdez-Solana, Adriana Castillo-Villanueva, Alfredo Téllez-Valencia, Erick Sierra-Campos, Miguel Flores-Ramos, Jesús Oria-Hernández, Claudia Avitia-Domínguez, Wolfgang Peti, Alicia Hernández-Campos, Hugo Jiménez-de Jesús, Mara Campos-Almazán, Kristiane Torgeson, Rafael Castillo, Sara T. Méndez
المصدر: Bioorganic & Medicinal Chemistry. 48:116418
مصطلحات موضوعية: Blood Glucose, Benzimidazole, Stereochemistry, Clinical Biochemistry, Phosphatase, Substituent, Pharmaceutical Science, Molecular Dynamics Simulation, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Molecular dynamics, Drug Discovery, medicine, Animals, Hypoglycemic Agents, Enzyme Inhibitors, Rats, Wistar, Molecular Biology, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Glucose Tolerance Test, Protein Tyrosine Phosphatase 1B, Rats, medicine.anatomical_structure, chemistry, Design synthesis, Drug Design, Molecular Medicine, Benzimidazoles, Female, Linker, Nucleus
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae52b432dc15ef5fb972d9c909b1e9bTest
https://doi.org/10.1016/j.bmc.2021.116418Test -
2
المصدر: Bioorganic & Medicinal Chemistry
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Phosphopeptides, Clinical Biochemistry, Pharmaceutical Science, Peptide, Protein tyrosine phosphatase, Biochemistry, Article, Peptide substrate, Substrate Specificity, 03 medical and health sciences, Drug Discovery, Biochemical testing, Humans, Peptide substrates, Amino Acid Sequence, Molecular Biology, ComputingMethodologies_COMPUTERGRAPHICS, Medicine(all), chemistry.chemical_classification, Protein Tyrosine Phosphatase, Non-Receptor Type 1, 030102 biochemistry & molecular biology, Phosphopeptide, Organic Chemistry, PTP1B, Protein Tyrosine Phosphatase 1B, 3. Good health, Protein tyrosine phosphatases, 030104 developmental biology, chemistry, Models, Chemical, Phosphoprotein, Molecular Medicine, Computational prediction, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c2d104a1b65b9ca95bcc3cf7b60a53Test
http://europepmc.org/articles/PMC4957924Test -
3
المؤلفون: Qunyi Li, Liu Peihong, Yongli Du, Jingkang Shen, Lianhua Song
المصدر: Bioorganic & Medicinal Chemistry. 23:7079-7088
مصطلحات موضوعية: Stereochemistry, Glucose uptake, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biocompatible Materials, CHO Cells, Crystallography, X-Ray, Biochemistry, Cell Line, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Cricetulus, Cricetinae, Drug Discovery, medicine, Animals, Insulin, Structure–activity relationship, Enzyme Inhibitors, Phosphorylation, Binding site, Phosphotyrosine, Molecular Biology, IC50, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Binding Sites, Chemistry, Organic Chemistry, Receptor, Insulin, Protein Structure, Tertiary, Molecular Docking Simulation, Glucose, Enzyme, Docking (molecular), Drug Design, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943b9625b4617f9c80cc6b4660f8bc6fTest
https://doi.org/10.1016/j.bmc.2015.09.024Test -
4
المؤلفون: Qunyi Li, Meng Zhang, Jingkang Shen, Yongli Du, Ling Hao
المصدر: Bioorganic & Medicinal Chemistry. 23:4891-4898
مصطلحات موضوعية: Phosphotyrosine binding, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Protein tyrosine phosphatase, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Humans, Enzyme Inhibitors, Molecular Biology, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Sulfonamides, Binding Sites, biology, Chemistry, Organic Chemistry, Protein Tyrosine Phosphatase 1B, Molecular Docking Simulation, Kinetics, Insulin receptor, Docking (molecular), Drug Design, biology.protein, Molecular Medicine, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7c41d1bd273c573a78d2a017f9c5f1Test
https://doi.org/10.1016/j.bmc.2015.05.032Test -
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المؤلفون: Wolfgang Peti, Rebecca Page
المصدر: Bioorganic & Medicinal Chemistry. 23:2781-2785
مصطلحات موضوعية: Clinical Biochemistry, Phosphatase, Allosteric regulation, Druggability, Pharmaceutical Science, Biochemistry, Article, Serine, Protein Phosphatase 1, Cyclosporin a, Drug Discovery, Phosphoprotein Phosphatases, Humans, Protein Interaction Domains and Motifs, Protein Interaction Maps, Tyrosine, Molecular Biology, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Substrate Interaction, Chemistry, Calcineurin, Organic Chemistry, Protein phosphatase 1, Molecular Docking Simulation, Drug Design, Molecular Medicine, Allosteric Site
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adf15e5d29f079750e0e37785aefa3bTest
https://doi.org/10.1016/j.bmc.2015.02.040Test -
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المؤلفون: Anja Schütz, Jörg Rademann, Stefan Wagner
المصدر: Bioorganic & Medicinal Chemistry. 23:2839-2847
مصطلحات موضوعية: Models, Molecular, Light, Peptidomimetic, Clinical Biochemistry, Pharmaceutical Science, Phenylalanine, Protein tyrosine phosphatase, Biochemistry, Dithiothreitol, chemistry.chemical_compound, Drug Discovery, Peptide synthesis, Humans, Moiety, Protein phosphorylation, Enzyme Inhibitors, Phosphotyrosine, Molecular Biology, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Phosphopeptide, Organic Chemistry, Combinatorial chemistry, chemistry, Molecular Medicine, Peptidomimetics, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e931482b5dd29e47f81e29680ae9e9cTest
https://doi.org/10.1016/j.bmc.2015.03.074Test -
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المؤلفون: Deiske A. Sumilat, Masaaki Ishikawa, Takahiro Nakazawa, Shiori Takahashi, Syu-ichi Kanno, Kazuyo Ukai, Ohgi Takahashi, Michio Namikoshi, Hiroyuki Yamazaki
المصدر: Bioorganic & Medicinal Chemistry. 23:797-802
مصطلحات موضوعية: Models, Molecular, Circular dichroism, Diene, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Polyketide, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Drug Discovery, Side chain, Animals, Humans, Molecular Biology, Cell Proliferation, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Biological Products, Bicyclic molecule, Organic Chemistry, Absolute configuration, Porifera, Enzyme, Diabetes Mellitus, Type 2, chemistry, Molecular Medicine, Enantiomer, Sesquiterpenes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc1c94f9ec9f53ccf053b5dc33319efTest
https://doi.org/10.1016/j.bmc.2014.12.049Test -
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المؤلفون: Orazio Taglialatela-Scafati, Lin-Fu Liang, Li-Xin Gao, Yue-Wei Guo, Jia Li
المساهمون: Liang, L. F., Gao, L. X., Li, J., Guo, Y, TAGLIALATELA SCAFATI, Orazio
المصدر: Bioorganic & Medicinal Chemistry. 21:5076-5080
مصطلحات موضوعية: Protein Tyrosine Phosphatase, Non-Receptor Type 1, Magnetic Resonance Spectroscopy, South china, Bicyclic molecule, Stereochemistry, Chemistry, Coral, Organic Chemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Anthozoa, Biochemistry, Protein Tyrosine Phosphatase 1B, Terpene, Structure-Activity Relationship, Drug Discovery, Sarcophyton trocheliophorum, Animals, Humans, Molecular Medicine, Diterpenes, Enzyme Inhibitors, Molecular Biology, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bb7d8f445cc3f8cbdf470216d4b65fTest
https://doi.org/10.1016/j.bmc.2013.06.043Test -
9
المؤلفون: Neha Rahuja, Pervez Ahmad, Lalit Prakash Gupta, Akhilesh K. Tamrakar, Swayam Prakash Srivastava, Arvind K. Srivastava, Siddharth Sharma, Atul Kumar
المصدر: Bioorganic & Medicinal Chemistry. 20:2172-2179
مصطلحات موضوعية: Blood Glucose, Male, Sucrose, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Streptozocin, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, Eating, Mice, chemistry.chemical_compound, Propiophenone, In vivo, Weight Loss, Drug Discovery, medicine, Animals, Hypoglycemic Agents, Potency, Rats, Wistar, Molecular Biology, Hypolipidemic Agents, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Propiophenones, Organic Chemistry, Streptozotocin, Lipids, In vitro, Rats, Mice, Inbred C57BL, Mechanism of action, chemistry, Molecular Medicine, medicine.symptom, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ad74ef6e9aa9b99b598be0f2080f57Test
https://doi.org/10.1016/j.bmc.2011.12.027Test -
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المؤلفون: Jayeon Kim, Phi Hung Nguyen, Joseph Tanyi Mbafor, Derek Tantoh Ndinteh, Won Keun Oh, Trong Tuan Dao, Do Tuan Phong
المصدر: Bioorganic & Medicinal Chemistry. 19:3378-3383
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Protein tyrosine phosphatase, Plant Roots, Biochemistry, Prenylation, Drug Discovery, Humans, Enzyme Inhibitors, Molecular Biology, Erythrina, Flavonoids, Protein Tyrosine Phosphatase, Non-Receptor Type 1, chemistry.chemical_classification, Erythrina abyssinica, biology, Chemistry, Circular Dichroism, Organic Chemistry, Biological activity, biology.organism_classification, Enzyme assay, Terpenoid, Enzyme, Enzyme inhibitor, Plant Bark, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4988df8d56457d5e5c6be8b75037bd3fTest
https://doi.org/10.1016/j.bmc.2011.04.037Test