المؤلفون: You-Min Hu, Yong-Yao Cui, Hui-Zhong Liu, Hong-Zhuan Chen, Liang Zhu, Yang Lu, Zhi-Peng Wang, Yin-Yao Niu

المصدر: Bioorganic & Medicinal Chemistry. 21:1234-1239

مصطلحات موضوعية: Male, Stereochemistry, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Muscarinic Antagonists, Biochemistry, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Ileum, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Animals, Heart Atria, Methylene, Molecular Biology, Receptor, Muscarinic M3, Receptor, Muscarinic M2, Organic Chemistry, Absolute configuration, Muscarinic antagonist, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Rats, chemistry, Toxicity, Molecular Medicine, Female, Enantiomer, Tropanes, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88737dec7894229aea4c70e2110246aTest
https://doi.org/10.1016/j.bmc.2012.12.052Test

المؤلفون: Jonathan A. Gordon, Richard K. Gordon, Apurba K. Bhattacharjee, Elizabeth Marek, Amy J. Campbell

المصدر: Bioorganic & Medicinal Chemistry. 17:3999-4012

مصطلحات موضوعية: Atropine, Quantitative structure–activity relationship, Molecular model, Stereochemistry, Guinea Pigs, Clinical Biochemistry, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Ether, Muscarinic Antagonists, Biochemistry, Cell Line, Ilium, chemistry.chemical_compound, Drug Discovery, Muscarinic acetylcholine receptor, Animals, Pancreas, Molecular Biology, Acetylcholine receptor, Molecular Structure, Hydrogen bond, Chemistry, Organic Chemistry, Rats, Quantum Theory, Molecular Medicine, Proton affinity, Propionates, Pharmacophore

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b139e0f380d8218ff24d937b2fc93c29Test
https://doi.org/10.1016/j.bmc.2009.04.001Test

المؤلفون: Y.C. Sunil Kumar, D. Asha, Kanchugarakoppal S. Rangappa, Manish Malviya, J. N. Narendra Sharath Chandra, M.N. Subhash

المصدر: Bioorganic & Medicinal Chemistry. 16:7095-7101

مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, Morpholino, medicine.drug_class, Arecoline, Scopolamine, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Inositol 1,4,5-Trisphosphate, Muscarinic Antagonists, Biochemistry, Muscarinic agonist, Structure-Activity Relationship, Alzheimer Disease, Internal medicine, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Animals, Learning, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Receptor, Muscarinic M1, Organic Chemistry, Muscarinic acetylcholine receptor M1, medicine.disease, Rats, Endocrinology, Molecular Medicine, Amnesia, Alzheimer's disease, Synaptosomes, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00463bd0037a309c7039d1a3c45d64b3Test
https://doi.org/10.1016/j.bmc.2008.06.053Test

المؤلفون: Carlo Melchiorre, Anna Minarini, Gabriella Marucci, Cristina Bellucci, Vincenzo Tumiatti, Michela Rosini, Carla Ghelardini, Michela Buccioni, Andrea Milelli

المساهمون: V. Tumiatti, A. Minarini, A. Milelli, M. Rosini, M. Buccioni, G. Marucci, C. Ghelardini, C. Bellucci, C. Melchiorre

المصدر: Bioorganic & Medicinal Chemistry. 15:2312-2321

مصطلحات موضوعية: Male, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Photoaffinity Labels, Biochemistry, Mice, Radioligand Assay, chemistry.chemical_compound, Vas Deferens, Cricetinae, Parietal Lobe, Drug Discovery, Muscarinic acetylcholine receptor M5, Muscarinic acetylcholine receptor, Polyamines, Methoctramine, Receptor, Cerebral Cortex, Molecular Structure, biology, PAIN, Receptors, Muscarinic, METHOCTRAMINE, Enzyme inhibitor, Acetylcholinesterase, Molecular Medicine, Rabbits, Acetylcholine, medicine.drug, Stereochemistry, Guinea Pigs, CHO Cells, Muscarinic Antagonists, Diamines, Structure-Activity Relationship, Cricetulus, Ileum, medicine, Animals, Humans, Heart Atria, Muscle, Skeletal, Molecular Biology, Acetylcholine receptor, Organic Chemistry, Muscarinic antagonist, Rats, chemistry, Butyrylcholinesterase, Drug Design, biology.protein, Cholinesterase Inhibitors

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5d0eaac9e4c5d07218cdcc36b402a4Test
https://doi.org/10.1016/j.bmc.2007.01.022Test

المؤلفون: Rodrigo Costa, Corinne Floyd, Maria C. M. Young, Vanderlan da Silva Bolzani, Claudio Viegas, Monica Santos Rocha, Carlos A. M. Fraga, Rafael Ferracini Cabral, Luisa S. B. Pimentel, Newton G. Castro, Eliezer J. Barreiro

المصدر: Bioorganic & Medicinal Chemistry. 13:4184-4190

مصطلحات موضوعية: Male, Stereochemistry, Scopolamine, Clinical Biochemistry, Pharmaceutical Science, Flowers, Muscarinic Antagonists, Pharmacognosy, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Alkaloids, Piperidines, Cassia, Drug Discovery, Senna spectabilis, Animals, Rats, Wistar, Molecular Biology, Butyrylcholinesterase, Plants, Medicinal, Molecular Structure, biology, Plant Extracts, Chemistry, Alkaloid, Organic Chemistry, Brain, biology.organism_classification, Acetylcholinesterase, Rats, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Amnesia, Cholinesterase Inhibitors, Piperidine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8305a2a20448f55a47abbe1b1cd5b4Test
https://doi.org/10.1016/j.bmc.2005.04.030Test

المؤلفون: T. Kendall Harden, Harold Kohn, Myoung Goo Kim, Erik T. Bodor

المصدر: Bioorganic & Medicinal Chemistry. 12:2357-2367

مصطلحات موضوعية: Aza Compounds, Bicyclic molecule, Chemistry, Ligand, Stereochemistry, Spectrum Analysis, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biological activity, Muscarinic Antagonists, Ligands, Biochemistry, Chemical synthesis, Enol, Bridged Bicyclo Compounds, chemistry.chemical_compound, Competitive antagonist, COS Cells, Drug Discovery, Muscarinic acetylcholine receptor, Animals, Molecular Medicine, Receptor, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128d3cb7991822830325b618172944c2Test
https://doi.org/10.1016/j.bmc.2004.02.016Test

المؤلفون: William J. Greenlee, William Billard, Herbert Binch, Lian-Yong Chen, Ruth A. Duffy, Charles Liu, Gordon Crosby, Stuart W. McCombie, John W. Clader, Jennifer Ford, Shengjian Li, Joseph A. Kozlowski, Gowei Zhou, Vice Susan F, Jean E. Lachowicz

المصدر: Bioorganic & Medicinal Chemistry. 12:319-326

مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Drug Evaluation, Preclinical, Biological Availability, Pharmaceutical Science, Carboxamide, CHO Cells, Muscarinic Antagonists, Pharmacology, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Piperidines, In vivo, Cricetinae, Drug Discovery, Muscarinic acetylcholine receptor, Avoidance Learning, medicine, Animals, Structure–activity relationship, ortho-Aminobenzoates, Molecular Biology, Receptor, Muscarinic M2, Dose-Response Relationship, Drug, Chemistry, Organic Chemistry, Antagonist, In vitro, Rats, Bioavailability, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fb6725ef949509463e302ecb37ec1fTest
https://doi.org/10.1016/j.bmc.2003.11.005Test

المؤلفون: Masanori Takadoi, Shiro Terashima, Kentaro Yamaguchi

المصدر: Bioorganic & Medicinal Chemistry. 11:1169-1186

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Muscarinic Antagonists, In Vitro Techniques, Naphthalenes, Binding, Competitive, Biochemistry, Chemical synthesis, Lactones, chemistry.chemical_compound, Alkaloids, Piperidines, Drug Discovery, Animals, Moiety, Furans, Molecular Biology, Cerebral Cortex, chemistry.chemical_classification, Receptor, Muscarinic M2, Organic Chemistry, Stereoisomerism, Muscarinic acetylcholine receptor M2, Receptors, Muscarinic, Rats, Quinuclidinyl Benzilate, Kinetics, chemistry, Himbacine, Molecular Medicine, Indicators and Reagents, Epimer, Stereoselectivity, Enantiomer, Lactone, Brain Stem

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4dcb715d0b35d2bdb1e4531b5c2acf0Test
https://doi.org/10.1016/s0968-0896Test(02)00665-x

المؤلفون: Serena Scapecchi, Fulvio Gualtieri, Rosanna Matucci, Gabriella Marucci, Dina Manetti, Cristina Bellucci, Michela Buccioni, Silvia Dei, Elisabetta Teodori, Maria Novella Romanelli, Piero Angeli

المصدر: Bioorganic & Medicinal Chemistry. 9:1165-1174

مصطلحات موضوعية: Atropine, Male, Agonist, Swine, medicine.drug_class, Stereochemistry, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Phenylpiperazine, Muscarinic Antagonists, In Vitro Techniques, Muscarinic Agonists, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Vas Deferens, Ileum, Drug Discovery, Muscarinic acetylcholine receptor, Agonistic behaviour, medicine, Animals, Receptor, Lung, Molecular Biology, Acetylcholine receptor, Cerebral Cortex, Receptor, Muscarinic M3, Receptor, Muscarinic M2, Chemistry, Myocardium, Receptor, Muscarinic M1, Organic Chemistry, Receptors, Muscarinic, Rats, Alkynes, Molecular Medicine, Rabbits, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df34c2e1dba76684f3a18cb747c64a8aTest
https://doi.org/10.1016/s0968-0896Test(00)00332-1

المؤلفون: Maurizio Recanatini, Nicola Solaroli, David Bryan, Silvia Vertuani, Stefano Manfredini, Ilaria Lampronti, Michael McKinney

المصدر: Bioorganic & Medicinal Chemistry. 8:1559-1566

مصطلحات موضوعية: Tertiary amine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, CHO Cells, Muscarinic Antagonists, Transfection, Biochemistry, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Drug Discovery, Muscarinic acetylcholine receptor, Animals, Humans, Structure–activity relationship, Amines, Cloning, Molecular, Receptor, Molecular Biology, Acetylcholine receptor, Oxadiazoles, Dose-Response Relationship, Drug, Organic Chemistry, Muscarinic acetylcholine receptor M3, Dioxolanes, Stereoisomerism, Muscarinic acetylcholine receptor M2, Receptors, Muscarinic, chemistry, Dioxolane, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491f2767f7b40e4eb23332273eec8641Test
https://doi.org/10.1016/s0968-0896Test(00)00092-4