Prioritization of the biomarkers to be analyzed in the French biomonitoring program
| العنوان: | Prioritization of the biomarkers to be analyzed in the French biomonitoring program |
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| المؤلفون: | Stéphanie Vandentorren, Robert Garnier, Clémence Fillol, Isabelle Momas, Louis Rachid Salmi, Jean-Ulrich Mullot, Céline Boudet |
| المساهمون: | Institut de Veille Sanitaire (INVS), Centre antipoison et de toxicovigilance (Paris) (CAPTV Paris), Université Paris Diderot - Paris 7 (UPD7)-Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, Laboratoire d'Analyses de Surveillance et d'Expertise de la Marine [Toulon] (LASEM), Service de Santé des Armées, Institut National de l'Environnement Industriel et des Risques (INERIS), Epidémiologie Environnementale : Impact Sanitaire des Pollutions (EA 4064), Université Paris Descartes - Paris 5 (UPD5), Epidémiologie et Biostatistique [Bordeaux], Université Bordeaux Segalen - Bordeaux 2-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Civs, Gestionnaire, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Université Bordeaux Segalen - Bordeaux 2 |
| المصدر: | Biomonitoring, Vol 1, Iss 1 (2014) Biomonitoring Biomonitoring, 2014, 1 (1), ⟨10.2478/bimo-2014-0010⟩ |
| بيانات النشر: | De Gruyter, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, Prioritization, Process management, Computer science, lcsh:Public aspects of medicine, Delphi method, lcsh:RA1-1270, Consensus method, Ranking (information retrieval), Round table, lcsh:Biology (General), Environmental protection, Human exposure, Biomonitoring, [SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health, Biomarker (medicine), Delphi process, Environmental epidemiology, computer, lcsh:QH301-705.5, Delphi, Biomarkers, computer.programming_language |
| الوصف: | The aim of this work was to develop a comprehensive prioritization method to select the biomarkers to be monitored in the French national biomonitoring program. The first step consisted in building an exhaustive list of biomarkers. The next step involved prioritizing the initial list of biomarkers according to specific scientific questions about human exposure to chemicals in the environment, and meet logistical, feasibility and budgetary constraints. The Delphi consensus method was used to prioritize biomarkers and was developed in three phases: i) the definition of relevant criteria for selecting biomarkers; ii) the prioritization of the biomarker list based on these criteria and iii) the validation of the list by the stakeholders. Among the eight relevant criteria for selecting biomarkers, hazard identification and social perception were the highest-rated and lowestrated criteria, respectively. After scoring each criterion for each group of biomarkers, and discussing the relative ranking of each group during a round table meeting, the final prioritized list obtained contained both historic (e.g. dioxins or lead) and emerging substances (e.g. phthalates, bisphenol A). Combining rigor and flexibility, our method has clearly helped to build a prioritized list shared and supported by many international actors. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2300-4606 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81e94cec112868dd2551949a58b8d5aTest http://www.degruyter.com/view/j/bimo.2014.1.issue-1/bimo-2014-0010/bimo-2014-0010.xml?format=INTTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a81e94cec112868dd2551949a58b8d5a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23004606 |
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