دورية أكاديمية
Post-operative functional neurological symptom disorder after anesthesia
| العنوان: | Post-operative functional neurological symptom disorder after anesthesia |
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| المؤلفون: | Ryan S. D’Souza, Matthew N.P. Vogt, Edwin H. Rho |
| المصدر: | Biomolecules & Biomedicine, Vol 20, Iss 3 (2020) |
| بيانات النشر: | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | Functional neurological symptom disorder, anesthesia, peri-operative period, psychogenic coma, psychogenic non-epileptic seizures, conversion paralysis, Biology (General), QH301-705.5 |
| الوصف: | A rare manifestation during the post-anesthetic period may include the occurrence of functional neurological symptom disorder (FNSD). FNSD is described as neurological symptoms that are not consistently explained by neurological or medical conditions. We report a case series consisting of six patients who underwent a general anesthetic at a tertiary referral hospital and experienced FNSD in the immediate post-anesthetic period. Life-threatening causes were excluded based on benign physical exam findings and knowledge of past history. Five of six cases manifested with FNSD only in the immediate post-operative setting after exposure to anesthesia, and never otherwise experienced these symptoms during their normal daily lives. MEDLINE and Google Scholar were searched through October 2019 using a highly-sensitive search strategy and identified 38 published cases of post-anesthetic FNSD. Meta-analysis of pooled clinical data revealed that a significant proportion of patients were females (86%), reported a history of psychiatric illness (49%), reported a prior history of FNSD (53%), and underwent general anesthesia as the primary anesthetic (93%). The majority of patients were exposed to diagnostic studies (66% received radiographic tests and 52% received electroencephalogram) as well as pharmacologic therapy (57%). While no deaths occurred, many patients had unanticipated admission to the hospital (53%) or to the intensive care unit (25%). These data may help inform the anesthesia literature on presentation, risk factors, and treatment outcomes of FNSD in the context of anesthetic administration. We contemplate whether anesthetic agents may predispose a vulnerable brain to manifest with involuntary motor and sensory control seen in FNSD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2831-0896 2831-090X |
| العلاقة: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/4646Test; https://doaj.org/toc/2831-0896Test; https://doaj.org/toc/2831-090XTest |
| DOI: | 10.17305/bjbms.2020.4646 |
| الوصول الحر: | https://doaj.org/article/90ba45165620488095ebbf0e4121e8aaTest |
| رقم الانضمام: | edsdoj.90ba45165620488095ebbf0e4121e8aa |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 28310896 2831090X |
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| DOI: | 10.17305/bjbms.2020.4646 |