The Diagnostic Ability of rs-DWI to Detect Subtle Acute Infarction Lesion in the Different Regions of the Brain and the Comparison between Different b-Values
| العنوان: | The Diagnostic Ability of rs-DWI to Detect Subtle Acute Infarction Lesion in the Different Regions of the Brain and the Comparison between Different b-Values |
|---|---|
| المؤلفون: | Jianzhong Yin, Wenzhen Zhu, Guoping Liu, Hongyan Ni, Shun Zhang, Liwu Zhang, Tanoj Bahadur Singh, Xiaoting Huo |
| المصدر: | BioMed Research International, Vol 2018 (2018) BioMed Research International |
| بيانات النشر: | Hindawi Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Frontal cortex, Article Subject, Infarction, lcsh:Medicine, Sensitivity and Specificity, General Biochemistry, Genetics and Molecular Biology, 030218 nuclear medicine & medical imaging, Lesion, 03 medical and health sciences, 0302 clinical medicine, Text mining, McNemar's test, Medicine, Humans, Prospective Studies, cardiovascular diseases, Aged, Diffusion weighting, General Immunology and Microbiology, business.industry, Echo-Planar Imaging, lcsh:R, Brain, General Medicine, Cerebral Infarction, Middle Aged, medicine.disease, Predictive value, True negative, Diffusion Magnetic Resonance Imaging, Female, Radiology, medicine.symptom, business, 030217 neurology & neurosurgery, Research Article |
| الوصف: | Objective. To evaluate the diagnostic ability of rs-DWI to detect subtle acute infarction lesion in the different regions of the brain in comparison to routine DWI and the comparison between different b-values. Method. 35 acute brain infarction patients were included. The subtle acute infarction lesions in ss-DWI and rs-DWI sequence were evaluated in 9 anatomical regions of the brain, and the ss-EPI DWI was also acquired with different b-values of 0, 1000, 2000, and 3000s/mm2. The McNemar test was performed for comparing the diagnostic ability of ss-DWI and rs-DWI and different b-values. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for the whole brain and in each anatomical region were calculated. Result. A total of 406 subtle acute infarction lesions were confirmed. The ss-DWI detected 338 subtle lesions, out of which 318 were true positive and 20 were false positive lesions. The rs-DWI detected 386 subtle lesions, out of which 385 were true positive lesions and 1 was true negative lesion. Sensitivity, specificity, positive predictive value, and negative predictive value in rs-DWI were better than ss-DWI in all anatomical regions of the brain. In the comparison of different b-values, b2000 was found better among b1000, b2000, and b3000. Conclusion. The rs-DWI offers a useful alternative to routine DWI for detecting the subtle acute infarctions, especially in the regions that are susceptible to distortion as in frontal cortex. In addition, high b-value can also provide benefit by increasing diffusion weighting but further raising can deteriorate image quality as SNR is decreased. |
| وصف الملف: | text/xhtml |
| اللغة: | English |
| تدمد: | 2314-6141 2314-6133 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da8afc9b64749a6366d577f388a0c50Test https://doaj.org/article/978f2f9413304c6eb5caf4674eb19bd9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3da8afc9b64749a6366d577f388a0c50 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23146141 23146133 |
|---|