نتائج البحث

1

TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy

المساهمون: Repositório da Universidade de Lisboa, [Canhão,H, Rodrigues,AM, Santos,MJ, Carmona-Fernandes,D, Polido-Pereira,J, Fonseca,JE] Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. [Canhão,H, Polido-Pereira,JA, Pereira Silva,JA, Fonseca,JE] Rheumatology Department, Hospital de Santa Maria (CHLN), Lisbon Academic Medical Centre, Lisbon, Portugal. [Canhão,H, Cui,J, Plenge,RM, Solomon,DH, Karlson,EW] Division of Rheumatology, Allergy and Immunology, Section of Clinical Sciences, Brigham and Women’s Hospital, Boston, USA. [Santos,MJ, Canas Silva,J] Rheumatology Department, Hospital Garcia de Orta, Almada, Portugal. [Bettencourt,BF, Rocha,FL, Bruges-Armas,J] SEEBMO, Hospital de Santo Espirito da Ilha Terceira, Azores, Portugal. [Bettencourt,BF, Bruges-Armas,J] Genetics & Arthritis Research Group (GARG), Institute for Molecular and Cell Biology (IBMC), Oporto, Portugal. [Costa,JA, Araujo,D] Rheumatology Department, Conde de Bertiandos Hospital (ULSAM), Ponte de Lima, Portugal. [Silva,C, Santos,H] Instituto Português de Reumatologia, Lisbon, Portugal. [Duarte,C, Da Silva,JAP] Rheumatology Department, Centro Hospitalar da Universidade de Coimbra, Coimbra, Portugal. [Cáliz,R] Rheumatology Department, Virgen de las Nieves University Hospital, Granada, Spain. [Filipescu,I] Rheumatology Department, University of Medicine and Pharmacy 'Iuliu Hatieganu', Cluj-Napoca, Romania. [Pimentel-Santos,F, Branco,J] CEDOC, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal. Rheumatology Department, Hospital de Egas Moniz (CHLO), Lisbon, Portugal. [Sainz,J] Genomic Oncology Area, GENYO Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain. [Plenge,RM] The Broad Institute of Harvard and MIT, Cambridge, MA, USA. [Solomon,DH] Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Boston, MA, USA., This work was supported by a grant from Harvard-Portugal Program HMSP-ICS/SAU-ICT/0002/2010. Daniel H. Solomon received support for this work from the NIH (K24-AR-055989). Elizabeth W. Karlson received support for this work from NIH (K24-AR-AR0524). Reuma.pt received unrestricted grants from Abbott, Bristol-Myers Squibb, Merck Sharp and Dohme, Pfizer, Roche, and UCB Pharma., NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Centro de Estudos de Doenças Crónicas (CEDOC)

المصدر: Digibug. Repositorio Institucional de la Universidad de Granada
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BioMed Research International
BioMed Research International, Vol 2015 (2015)

وصف الملف: text/xhtml; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1995f888fe9e97d0eeddac9b8e367547Test

2

Unexpected Lack of Deleterious Effects of Uranium on Physiological Systems following a Chronic Oral Intake in Adult Rat

المؤلفون: Anaïs Paulard, Yseult Kern, Jeanne Loyen, Yann Gueguen, Patrick Gourmelon, Isabelle Dublineau, Maâmar Souidi, Audrey Monin, Stéphane Grison, Caroline Rouas, Jean Marc Bertho, Olivia Delissen, Jocelyne Aigueperse, Line Manens, Philippe Lestaevel

المساهمون: PRP-HOM/SRBE/LRTOX, Institut de Radioprotection et de Sûreté Nucléaire (IRSN)

المصدر: BioMed Research International
BioMed Research International, 2014, 2014, ⟨10.1155/2014/181989⟩
BioMed Research International, Vol 2014 (2014)

مصطلحات موضوعية: Male, uranium 238, Aging, food intake, uranium 234, uranium 235, Physiology, animal cell, Weight Gain, Antioxidants, Rats, Sprague-Dawley, Choline, multidrug resistance protein 1, transforming growth factor beta, tumor necrosis factor alpha, Sprague Dawley rat, adult, glutathione transferase A2, General Medicine, Uranium, 6. Clean water, 3. Good health, xenobiotic agent, Cholesterol, Organ Specificity, erythrocyte count, Administration, monocyte chemotactic protein 1, cholestanetriol 26 monooxygenase, Oral, inorganic chemicals, Article Subject, Drinking, biological activity, thrombocyte count, liver, General Biochemistry, Genetics and Molecular Biology, animal tissue, Humans, human, lymphocyte count, intestine, entorhinal cortex, lcsh:R, Hematopoiesis, cytochrome P450 2C11, chemistry, cholesterol metabolism, Sprague-Dawley, Tolerable daily intake, leukocyte count, antioxidant, [SDV]Life Sciences [q-bio], oral drug administration, lcsh:Medicine, Administration, Oral, immunology, Toxicology, chemistry.chemical_compound, Depleted uranium, membrane protein, rat, animal, messenger RNA, article, fluid intake, xenobiotic metabolism, Intestines, flt3 ligand protein, Toxicity, medicine.symptom, cytochrome P450 3A2, Research Article, multidrug resistance associated protein 2, kidney, brain, animal experiment, chemistry.chemical_element, Biology, hematopoietic cell, long term exposure, Xenobiotics, blood, organ, medicine, Animals, controlled study, nonhuman, General Immunology and Microbiology, drinking water, antibody specificity, Membrane Proteins, Feeding Behavior, Rats, Blood Cell Count, drug effects, physiology, gene expression, interleukin 10, Xenobiotic, metabolism, Weight gain