التفاصيل البيبلوغرافية
| العنوان: |
Nickel exposure and plasma levels of biomarkers for assessing oxidative stress in nickel electroplating workers. |
| المؤلفون: |
Tsao, Yu-Chung1,2,3,4 (AUTHOR) eusden@gmail.com, Gu, Po-Wen4,5 (AUTHOR), Liu, Su-Hsun1,3,4 (AUTHOR) eusden@gmail.com, Tzeng, I-Shiang1,6,7 (AUTHOR) eusden@gmail.com, Chen, Jau-Yuan3,4 (AUTHOR), Luo, Jiin-Chyuan John1,4 (AUTHOR) eusden@gmail.com |
| المصدر: |
Biomarkers. Jul2017, Vol. 22 Issue 5, p455-460. 6p. |
| مصطلحات موضوعية: |
*BIOMARKERS, *OXIDATIVE stress, *OXIDATION-reduction reaction, *BIOCHEMISTRY, PHYSIOLOGICAL effects of nickel |
| مستخلص: |
Context:The mechanism of nickel-induced pathogenesis remains elusive. Objective:To examine effects of nickel exposure on plasma oxidative and anti-oxidative biomarkers. Materials and methods:Biomarker data were collected from 154 workers with various levels of nickel exposure and from 73 controls. Correlations between nickel exposure and oxidative and anti-oxidative biomarkers were determined using linear regression models. Results:Workers with a exposure to high nickel levels had significantly lower levels of anti-oxidants (glutathione and catalase) than those with a lower exposure to nickel; however, only glutathione showed an independent association after multivariable adjustment. Discussion and conclusion:Exposure to high levels of nickel may reduce serum anti-oxidative capacity. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
