التفاصيل البيبلوغرافية
| العنوان: |
New York Heart Association class versus amino-terminal pro-B type natriuretic peptide for acute heart failure prognosis. |
| المؤلفون: |
Baggish, Aaron L., van Kimmenade, Roland R. J., Pinto, Yigal, Richards, A. Mark, Lainchbury, John, Bayes-Genis, Antoni, Santaló, Miquel, Ordonez-Llanos, Jordi, Januzzi, James L. |
| المصدر: |
Biomarkers; Jun2010, Vol. 15 Issue 4, p307-314, 8p, 2 Charts, 3 Graphs |
| مصطلحات موضوعية: |
HEART failure, HEART diseases, ATRIAL natriuretic peptides, PROGNOSIS, DISEASE risk factors |
| مستخلص: |
Background: The prognostic value of the New York Heart Association classification (NYHAC) in acutely decompensated heart failure (ADHF) is unknown. Objectives: We sought to determine the relative value of NYHAC among patients with concomitantly measured amino-terminal pro-B type natriuretic peptide (NT-proBNP) at presentation with ADHF. Materials and methods: NYHAC was determined for 720 patients with ADHF and 1-year mortality status was examined. Cox-proportional hazards analysis compared the prognostic accuracy of NYHAC with other ADHF risk measures. Results: NYHAC had a significant univariate association with 1-year mortality status (HR 1.41, 95% confidence interval (CI) 1.03–1.94; p = 0.03) but was not a significant predictor of death in a multivariable model that included NT-proBNP (HR 2.14; 95% CI 1.65–2.81, p < 0.001). Conclusions: In contrast to objective measures such as NT-proBNP, the NYHAC appears to provide limited prognostic information among individuals with ADHF. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
