دورية أكاديمية
Ultra-High Contrast MRI: Using Divided Subtracted Inversion Recovery (dSIR) and Divided Echo Subtraction (dES) Sequences to Study the Brain and Musculoskeletal System
| العنوان: | Ultra-High Contrast MRI: Using Divided Subtracted Inversion Recovery (dSIR) and Divided Echo Subtraction (dES) Sequences to Study the Brain and Musculoskeletal System |
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| المؤلفون: | Daniel Cornfeld, Paul Condron, Gil Newburn, Josh McGeown, Miriam Scadeng, Mark Bydder, Mark Griffin, Geoffrey Handsfield, Meeghage Randika Perera, Tracy Melzer, Samantha Holdsworth, Eryn Kwon, Graeme Bydder |
| المصدر: | Bioengineering, Vol 11, Iss 5, p 441 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Technology LCC:Biology (General) |
| مصطلحات موضوعية: | MRI, contrast, traumatic brain injury, white matter, ultrashort-T2*, fascia, Technology, Biology (General), QH301-705.5 |
| الوصف: | Divided and subtracted MRI is a novel imaging processing technique, where the difference of two images is divided by their sum. When the sequence parameters are chosen properly, this results in images with a high T1 or T2 weighting over a small range of tissues with specific T1 and T2 values. In the T1 domain, we describe the implementation of the divided Subtracted Inversion Recovery Sequence (dSIR), which is used to image very small changes in T1 from normal in white matter. dSIR has shown widespread changes in otherwise normal-appearing white matter in patients suffering from mild traumatic brain injury (mTBI), substance abuse, and ischemic leukoencephalopathy. It can also be targeted to measure small changes in T1 from normal in other tissues. In the T2 domain, we describe the divided echo subtraction (dES) sequence that is used to image musculoskeletal tissues with a very short T2*. These tissues include fascia, tendons, and aponeuroses. In this manuscript, we explain how this contrast is generated, review how these techniques are used in our research, and discuss the current challenges and limitations of this technique. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2306-5354 |
| العلاقة: | https://www.mdpi.com/2306-5354/11/5/441Test; https://doaj.org/toc/2306-5354Test |
| DOI: | 10.3390/bioengineering11050441 |
| الوصول الحر: | https://doaj.org/article/628502e0a3d44c67a78b71f1102eb468Test |
| رقم الانضمام: | edsdoj.628502e0a3d44c67a78b71f1102eb468 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23065354 |
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| DOI: | 10.3390/bioengineering11050441 |