Oncosuppressive functions of tribbles pseudokinase 3
| العنوان: | Oncosuppressive functions of tribbles pseudokinase 3 |
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| المؤلفون: | Tatiana Erazo, David Dávila, Endre Kiss-Toth, Jose M. Lizcano, Guillermo Velasco, María Salazar, Mar Lorente, Alba Orea-Soufi, Arkaitz Carracedo |
| المصدر: | Biochemical Society Transactions. 43:1122-1126 |
| بيانات النشر: | Portland Press Ltd., 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Apoptosis, Cell Cycle Proteins, Computational biology, Protein Serine-Threonine Kinases, Biology, Models, Biological, Biochemistry, Cell biology, Repressor Proteins, TRIB3, Neoplasms, Autophagy, Humans, Proto-Oncogene Proteins c-akt, Endocannabinoids, Protein Binding, Signal Transduction |
| الوصف: | Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression. |
| تدمد: | 1470-8752 0300-5127 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f914429cc85ba5fa1922050c2ef8d68Test https://doi.org/10.1042/bst20150124Test |
| رقم الانضمام: | edsair.doi.dedup.....4f914429cc85ba5fa1922050c2ef8d68 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14708752 03005127 |
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