Mitochondria and regulated tyrosine nitration
| العنوان: | Mitochondria and regulated tyrosine nitration |
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| المؤلفون: | Kulwant S. Aulak, Dennis J. Stuehr, Thomas Koeck |
| المصدر: | Biochemical Society Transactions. 33:1399 |
| بيانات النشر: | Portland Press Ltd., 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Metabolism, Mitochondrion, Biology, medicine.disease_cause, Biochemistry, Nitric oxide, chemistry.chemical_compound, Multicellular organism, Signalling, chemistry, Nitration, medicine, Homeostasis, Oxidative stress |
| الوصف: | The conditions of the cellular microenvironment in complex multicellular organisms fluctuate, enforcing permanent adaptation of cells at multiple regulatory levels. Covalent post-translational modifications of proteins provide the short-term response tools for cellular adjustment and growing evidence supports the possibility that protein tyrosine nitration is part of this cellular toolkit and not just a marker for oxidative damage. We have demonstrated that protein tyrosine nitration fulfils the major criteria for signalling and suggest that the normally highly regulated process may lead to disease upon excessive or inappropriate nitration. |
| تدمد: | 1470-8752 0300-5127 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::45a5f17b80514cdcf8cd44651e101e8dTest https://doi.org/10.1042/bst20051399Test |
| رقم الانضمام: | edsair.doi...........45a5f17b80514cdcf8cd44651e101e8d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14708752 03005127 |
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