Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds
العنوان: | Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds |
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المؤلفون: | Juqing Song, Guanglin Zhu, Xuetao Shi, Lin Wang, Yingjun Wang, Huichang Gao, Nanying Li |
المصدر: | Bio-Design and Manufacturing. 1:254-264 |
بيانات النشر: | Springer Science and Business Media LLC, 2018. |
سنة النشر: | 2018 |
مصطلحات موضوعية: | Scaffold, Materials science, Materials Science (miscellaneous), Biomedical Engineering, Nanotechnology, Nanofiber scaffold, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Industrial and Manufacturing Engineering, Bone tissue engineering, Electrospinning, 0104 chemical sciences, Tissue engineering, Electrospun nanofibers, Nanofiber, Human fetal, 0210 nano-technology, Biotechnology |
الوصف: | Inspired by the constitution of things in the natural world, three-dimensional (3D) nanofiber scaffold/cells complex was constructed via the combination of electrospinning technology and origami techniques. The nanofiber boxes prepared by origami provided a limited space for the layer-by-layer nanofiber films, and the human fetal osteoblasts (hFOBs) seeded on the both sides of the nanofiber films were expected to facilitate the bonding of the adjacent nanofiber films through the secretion of extracellular matrix. Specifically, the hFOBs presented 3D distribution in the nanofiber scaffold, and they can stretch across the gaps between the adjacent nanofiber films, forming the cell layers and filling the whole 3D nanofiber scaffold. Eventually, a 3D block composed of electrospun nanofiber scaffold and cells was obtained, which possesses potential applications in bone tissue engineering. Interestingly, we also created 3D nanofiber structures that range from simple forms to intricate architectures via origami, indicating that the combination of electrospinning technology and origami techniques is a feasible method for the 3D construction of tissue engineering scaffolds. |
تدمد: | 2522-8552 2096-5524 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::fcda9ee8e430d5e5c060e6e521d03d9fTest https://doi.org/10.1007/s42242-018-0027-9Test |
حقوق: | CLOSED |
رقم الانضمام: | edsair.doi...........fcda9ee8e430d5e5c060e6e521d03d9f |
قاعدة البيانات: | OpenAIRE |
تدمد: | 25228552 20965524 |
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