دورية أكاديمية
Cinnamon extract supplementation improves inflammation and oxidative stress induced by acrylamide: An experimental animal study
| العنوان: | Cinnamon extract supplementation improves inflammation and oxidative stress induced by acrylamide: An experimental animal study |
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| المؤلفون: | Fatemeh Haidari, Majid Mohammadshahi, Behnaz Abiri, Mehdi Zarei, Mojdeh Fathi |
| المصدر: | Avicenna Journal of Phytomedicine, Vol 10, Iss 3, Pp 243-252 (2020) |
| بيانات النشر: | Mashhad University of Medical Sciences, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | cinnamon extract, acrylamide, oxidative stress, liver enzyme, inflammation, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | Objective: Toxic effects of acrylamide on body organs incline researches to prevent or decrease these effects. The objective of the present study was to evaluate the effects of cinnamon extract (CE) supplementation on inflammation and oxidative stress induced by acrylamide in rats. Materials and Methods: Thirty two rats were divided into four groups as follow 1) The control group received distilled water, 2) Acrylamide- intoxicated group was administrated with 35 ml/kg/day acrylamide for two weeks, 3) Acrylamide- intoxicated rats treated with CE 250 mg/kg/day for 28 days, and 4) Acrylamide- intoxicated rats treated with CE 500 mg/kg day for 28 days. Fasting blood sample was obtained for subsequent analysis. Results: The results showed that acrylamide- intoxicated group had significantly higher levels of malondialdehyde, tumor necrosis factor alpha, high sensitive C reactive protein, leptin and alanine transaminase (p0.05). Conclusion: This study suggests that cinnamon extract may potentially be effective as a dietary source of bioactive compounds for managing acrylamide intoxication. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2228-7930 2228-7949 |
| العلاقة: | http://ajp.mums.ac.ir/article_13899_880e554cd07e44bc660d92f12a6da180.pdfTest; https://doaj.org/toc/2228-7930Test; https://doaj.org/toc/2228-7949Test |
| DOI: | 10.22038/ajp.2019.13899 |
| الوصول الحر: | https://doaj.org/article/d1ff76cb01c847c980e6dfd6e9cab422Test |
| رقم الانضمام: | edsdoj.1ff76cb01c847c980e6dfd6e9cab422 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22287930 22287949 |
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| DOI: | 10.22038/ajp.2019.13899 |