Autophagy in immunity
| العنوان: | Autophagy in immunity |
|---|---|
| المؤلفون: | Xu-jie Zhou, Hong Zhang |
| المصدر: | Autophagy. 8:1286-1299 |
| بيانات النشر: | Informa UK Limited, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Inflammation, Autoimmune disease, Antigen Presentation, Multiple sclerosis, Autophagy, Immunity, Review, Cell Biology, Vitiligo, Biology, medicine.disease, medicine.disease_cause, Acquired immune system, Models, Biological, Autoimmune Diseases, Autoimmunity, Lymphocyte homeostasis, Immunology, medicine, Animals, Humans, skin and connective tissue diseases, Molecular Biology |
| الوصف: | Autophagy is now emerging as a spotlight in trafficking events that activate innate and adaptive immunity. It facilitates innate pathogen detection and antigen presentation, as well as pathogen clearance and lymphocyte homeostasis. In this review, we first summarize new insights into its functions in immunity, which underlie its associations with autoimmunity. As some lines of evidence are emerging to support its role in autoimmune and autoinflammatory diseases, we further discuss whether and how it affects autoimmune diseases including systemic lupus erythematosus, rheumatoid arthritis, diabetes mellitus and multiple sclerosis, as well as autoinflammatory diseases, such as Crohn disease and vitiligo. |
| تدمد: | 1554-8635 1554-8627 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2437e4143ce7c08fd6ffe3ab31c6dedTest https://doi.org/10.4161/auto.21212Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f2437e4143ce7c08fd6ffe3ab31c6ded |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15548635 15548627 |
|---|