دورية أكاديمية
Differences in COVID-19 Outcomes Among Patients With Type 1 Diabetes: First vs Later Surges
| العنوان: | Differences in COVID-19 Outcomes Among Patients With Type 1 Diabetes: First vs Later Surges |
|---|---|
| المؤلفون: | Gallagher, Mary Pat, Rompicherla, Saketh, Ebekozien, Osagie, Wilkes, Meredith, Antal, Zoltan, Feuer, Alexis Jamie, Rioles, Nicole, Noor, Nudrat, Gabriel, Liana, O’Malley, Grenye, Golden, Lauren, Alonso, G. Todd, Ospelt, Emma, Odugbesan, Ori, Lyons, Sarah K., Mungmode, Ann, Prahalad, Priya, Clements, Mark, Neyman, Anna, Demeterco-Berggren, Carla, Rapaport, Robert |
| المساهمون: | Pediatrics, School of Medicine |
| المصدر: | Author |
| بيانات النشر: | MDedge |
| سنة النشر: | 2022 |
| المجموعة: | Indiana University - Purdue University Indianapolis: IUPUI Scholar Works |
| مصطلحات موضوعية: | COVID-19, type 1 diabetes, SARS-CoV-2 |
| الوصف: | Background Outcomes of the novel coronavirus SARS-CoV-2 (COVID-19) have improved throughout the pandemic. However, whether outcomes of COVID-19 in the type 1 diabetes (T1D) population improved over time is unknown. Therefore, we aim to investigate differences in COVID-19 outcomes for patients with T1D in the US. Method We analyzed data collected via a registry of patients with T1D and COVID-19 from 56 sites between April 2020 and January 2021. First, we grouped cases into First Surge (04/09/2020 - 07/31/2020, n=188) and Late Surge (08/01/2020 - 01/31/2021, n=410). Then, we compared outcomes between both groups using descriptive statistics and logistic regression models. Results Adverse outcomes were more frequent during the first surge including Diabetic Ketoacidosis (32% versus 15%, p<0.001), severe hypoglycemia (4% versus 1%, p=0.04) and hospitalization (52% versus 22%, p<0.001). The First surge cases were older (28 +/- 18.8 years versus 18.8 +/- 11.1 years, p<0.001), had higher hemoglobin A1c (HbA1c) levels (Median (IQR): 9.3 (4.0) versus 8.4(2.8), <0.001) and use public insurance (n(%): 107 (57) versus 154 (38), p <0.001). There were five times increased odds of hospitalization for adults (OR 5.01 (2.11,12.63) in the first surge compared to the late surge. Conclusion COVID-19 cases among patients with T1D reported during the first surge had a higher proportion of adverse outcomes than those presented in a later surge. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Journal of Clinical Outcomes Management; Gallagher MP., et al. (2022). Differences in COVID-19 Outcomes Among Patients With Type 1 Diabetes: First vs Later Surges. Journal of Clinical Outcomes Management, 29(1). https://doi.org/10.12788/jcom.0084Test; https://hdl.handle.net/1805/32031Test |
| الإتاحة: | https://doi.org/10.12788/jcom.0084Test https://hdl.handle.net/1805/32031Test |
| حقوق: | Publisher Policy |
| رقم الانضمام: | edsbas.BB93C704 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |