التفاصيل البيبلوغرافية
| العنوان: |
Analysis of Vascular Gene Expression in Arthritic Synovium by Laser- Mediated Microdissection. |
| المؤلفون: |
Hashimoto, Atsushi1,2, Tarner, Ingo H.1,2 i.tarner@kerckhoff-klinik.de, Bohle, Rainer M.1, Gaumann, Andreas3, Manetti, Mirko4,5, Distler, Oliver6, Steinmeyer, Jürgen7, Ulfgren, Ann-Kristin8, Schulz, Andreas1, Gay, Steffen6, Müller-Ladner, Ulf1,2, Neumann, Elena1,2 |
| المصدر: |
Arthritis & Rheumatism. Apr2007, Vol. 56 Issue 4, p1094-1105. 12p. 3 Black and White Photographs, 2 Charts, 3 Graphs. |
| مصطلحات موضوعية: |
*NEOVASCULARIZATION, *BLOOD-vessel development, *SYNOVIAL membranes, *RHEUMATOID arthritis, *OSTEOARTHRITIS, *GENE expression, *RHEUMATOLOGY |
| مستخلص: |
This article discusses findings of a study, which analyzed the specific synovial vascular expression profiles of several angiogenesis-related genes as well as CD82 in rheumatoid arthritis (RA) compared with osteoarthritis (OA). A key mechanism in the pathogenesis of RA is angiogenesis. Comparing messenger RNA (mRNA) or protein expression in RA synovial tissue and a control disease is a commonly used method for investigating differential gene expression. |
| قاعدة البيانات: |
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