Herpesvirus 8 Inclusions in Primary Effusion Lymphoma
العنوان: | Herpesvirus 8 Inclusions in Primary Effusion Lymphoma |
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المؤلفون: | S deVos, G Hanson, Joseph F. Baker, H Asou, I P Shintaku, Jonathan W. Said, H P Koeffler, Ethel Cesarman, Roland G. Nador |
المصدر: | Archives of Pathology & Laboratory Medicine. 123:257-260 |
بيانات النشر: | Archives of Pathology and Laboratory Medicine, 1999. |
سنة النشر: | 1999 |
مصطلحات موضوعية: | Pathology, medicine.medical_specialty, biology, T cell, General Medicine, Gene rearrangement, medicine.disease_cause, biology.organism_classification, medicine.disease, Phenotype, Herpesviridae, Virus, Pathology and Forensic Medicine, Medical Laboratory Technology, medicine.anatomical_structure, Alphaherpesvirinae, medicine, biology.protein, Primary effusion lymphoma, Antibody |
الوصف: | We describe a case of primary effusion lymphoma with T-cell phenotype, mixed genotype, and intranuclear herpesvirus inclusions visible with the light microscope. Cells were studied by immunohistochemical analysis, in situ hybridization, immunoglobulin and T-cell receptor gene rearrangement, and polymerase chain reaction. Primary effusion lymphoma cells with T-cell phenotype revealed herpesvirus 8 inclusions predominantly seen in apoptotic cells, suggesting that productive viral infection is associated with cell death. Clinical features were typical of primary effusion lymphoma. Cytologic, molecular genetic, and phenotypic features demonstrated a unique variant of primary effusion lymphoma. |
تدمد: | 1543-2165 0003-9985 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::ab1d7af4e24de52364a3d0e7de655e6eTest https://doi.org/10.5858/1999-123-0257-hiipelTest |
رقم الانضمام: | edsair.doi...........ab1d7af4e24de52364a3d0e7de655e6e |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15432165 00039985 |
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