التفاصيل البيبلوغرافية
| العنوان: |
Primary Cutaneous Follicle Center Lymphoma. |
| المؤلفون: |
Skala, Stephanie L.1, Hristov, Boris2,3, Hristov, Alexandra C.1 ahristov@med.umich.edu |
| المصدر: |
Archives of Pathology & Laboratory Medicine. Nov2018, Vol. 142 Issue 11, p1313-1321. 9p. 6 Color Photographs, 2 Charts. |
| مصطلحات موضوعية: |
*SKIN tumors, *B cell lymphoma, *DIFFERENTIAL diagnosis, *HAIR follicles, *IMMUNOHISTOCHEMISTRY, *IMMUNOPHENOTYPING, *GENETIC testing, *GENETICS, *DIAGNOSIS, *PROGNOSIS |
| مستخلص: |
* Context.--Primary cutaneous follicle center lymphoma is a low-grade B-cell lymphoma that is limited to the skin at diagnosis. It has a differential diagnosis that includes systemic/nodal follicular lymphoma secondarily involving the skin; primary cutaneous diffuse large B-cell lymphoma leg type; reactive lymphoid hyperplasia; and primary cutaneous marginal zone lymphoma. Objective.--To review the clinical, morphologic, immunophenotypic, and genetic features of primary cutaneous follicle center lymphoma; its differential diagnosis; and the evidence that supports use of immunohistochemistry and genetic testing in the diagnosis and prognosis of this entity. Data Sources.--Pertinent literature regarding cutaneous B-cell lymphomas is summarized and University of Michigan cases are used to highlight characteristics of primary cutaneous follicle center lymphoma. Conclusions.--Primary cutaneous follicle center lymphoma is a low-grade B-cell lymphoma with distinctive features, although some cases may have elements that overlap with other lymphomas, complicating interpretation. [ABSTRACT FROM AUTHOR] |
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