Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship?
| العنوان: | Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship? |
|---|---|
| المؤلفون: | Naglaa Agamia, Tamer Abou Youssif, Amr Magdy El-Abd, Abeer El-Hadidy |
| المصدر: | Arab Journal of Urology |
| بيانات النشر: | Elsevier, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, DHT, dihydrotestosterone, Urology, BMI, body mass index, education, HDL, high-density lipoprotein, 030232 urology & nephrology, CVD, cardiovascular disease, urologic and male genital diseases, AGA, androgenetic alopecia, Gastroenterology, Prostatic Disorders Original article, 030207 dermatology & venereal diseases, 03 medical and health sciences, HbA1c, glycosylated haemoglobin, 0302 clinical medicine, Internal medicine, medicine, In patient, FBS, fasting blood sugar, Androgenetic alopecia, reproductive and urinary physiology, ESR, erythrocyte sedimentation rate, Benign prostatic hyperplasia, medicine.diagnostic_test, biology, business.industry, Incidence (epidemiology), C-reactive protein, Hyperplasia, medicine.disease, Cardiovascular risk, Metabolic syndrome, female genital diseases and pregnancy complications, body regions, Endocrinology, Erythrocyte sedimentation rate, Dihydrotestosterone, biology.protein, CRP, C-reactive protein, business, Body mass index, medicine.drug |
| الوصف: | Objective To evaluate the incidence of benign prostatic hyperplasia (BPH) and metabolic syndrome in patients with androgenetic alopecia (AGA) in comparison with those with no AGA, as several previous studies have reported inconsistent results of an association between metabolic syndrome and BPH with AGA. Patients, subjects and methods This cross-sectional study included 400 participants, divided into 300 patients diagnosed with AGA, with different grades according to Norwood–Hamilton classification, and 100 control subjects with no AGA. Criteria for diagnosis of metabolic syndrome according to Adult Treatment Panel-III criteria (waist circumference, blood pressure, fasting blood sugar, high-density lipoprotein and triglycerides), as well as criteria for diagnosis of BPH (prostatic volume, urine flow, and prostate-specific antigen) were assessed in all patients and compared with the control subjects. Results There were significant differences between the AGA and no-AGA groups for the following variables: waist circumference, body mass index, fibrinogen level, fasting blood sugar, cholesterol, C-reactive protein, erythrocyte sedimentation rate, and glycosylated haemoglobin. There was a significant difference in number of patients with AGA manifesting criteria of metabolic syndrome (51% vs 28%), as well as BPH diagnostic criteria (36% vs 6.8%) compared with the control subjects. Both BPH and metabolic syndrome were shown to be significant independent variables associated with AGA. Conclusions Dermatologists, urologists, and primary care physicians should monitor patients with early onset AGA for the development of urinary symptoms, to permit an earlier diagnosis of BPH; and for metabolic syndrome symptoms, to permit early diagnosis of cardiovascular risk factors. |
| اللغة: | English |
| تدمد: | 2090-5998 2090-598X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadf907b8a86b9c331e6b96cc53cdf83Test http://europepmc.org/articles/PMC4963145Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....eadf907b8a86b9c331e6b96cc53cdf83 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20905998 2090598X |
|---|