دورية أكاديمية

Dynamics of liposomes gene vectors studied by anelastic spectroscopy.

التفاصيل البيبلوغرافية
العنوان: Dynamics of liposomes gene vectors studied by anelastic spectroscopy.
المؤلفون: Castellano, C., Pozzi, D., Caracciolo, G., Cantelli, R.
المصدر: Applied Physics Letters; 9/29/2003, Vol. 83 Issue 13, p2701, 3p, 1 Graph
مصطلحات موضوعية: BILAYER lipid membranes, SPECTRUM analysis
مستخلص: The anelastic spectra of synthetic liposomes interesting for gene transfection have been measured in a wide temperature range; in particular, we have studied the cationic/neutral lipid mixture di-oleoyl trimethylammonium propane/di-oleoyl phosphatidylethanolamine at different molar ratios. This technique has been applied on thin films of biological samples deposited on a solid substrate like Si <100>. We have evidenced the presence of two relaxation processes around and below 200 K, likely connected with a cooperative dynamics of the water plus membrane system. In particular, the process centered at 198 K results to be clearly a favorite by the presence of two different lipidic species. © 2003 American Institute of Physics. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00036951
DOI:10.1063/1.1611651