دورية أكاديمية

Biochemical and inflammatory parameters in intensive care unit and nonintensive care unit COVID-19 patients – A retrospective study

التفاصيل البيبلوغرافية
العنوان: Biochemical and inflammatory parameters in intensive care unit and nonintensive care unit COVID-19 patients – A retrospective study
المؤلفون: Muragendraswami N Astagimath, Raviraja Aryapu, Suman Doddamani
المصدر: Apollo Medicine, Vol 19, Iss 1, Pp 16-19 (2022)
بيانات النشر: Wolters Kluwer Medknow Publications, 2022.
سنة النشر: 2022
المجموعة: LCC:Medicine
مصطلحات موضوعية: covid-19, d-dimer, ferritin, troponin i, Medicine
الوصف: Background: COVID-19 presents with varied clinical presentations. Most of the patients have a good prognosis, but some patients rapidly progress to severe disease. Hence, early identification of severity becomes important. Aims and Objectives: This study aimed to compare the ferritin, troponin I, and D-dimer in intensive care unit (ICU) (severe) and non-ICU (nonsevere) patients of COVID-19. Materials and Methods: Data were collected from COVID-19 laboratory (n = approximately 2700). The patients were divided into ICU and non-ICU group. Ferritin and troponin I were estimated by chemiluminescence immunoassay and D-dimer was estimated by turbidimetric immunoassay. Results: Troponin I levels were comparable between the groups. Ferritin was elevated (P = 0.0001) in ICU patients compared to non-ICU patients. The levels of D-dimer were increased (P < 0.0001) in the ICU group compared to the non-ICU group. Conclusion: Despite the fact that troponin I may not be a decent indicator for the seriousness of the infection, it might be of use in patients with cardiovascular risk factors. Raised levels of ferritin might be a significant marker that demonstrates the chance of requiring escalated care for the COVID-19 patients. D-dimer can be used as a judicious marker for suggesting the severity and prognosis of the disease.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0976-0016
2213-3682
العلاقة: http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=1;spage=16;epage=19;aulast=AstagimathTest; https://doaj.org/toc/0976-0016Test; https://doaj.org/toc/2213-3682Test
DOI: 10.4103/am.am_133_21
الوصول الحر: https://doaj.org/article/b3233cf0bd244f2885e59da02e53f162Test
رقم الانضمام: edsdoj.b3233cf0bd244f2885e59da02e53f162
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:09760016
22133682
DOI:10.4103/am.am_133_21