التفاصيل البيبلوغرافية
| العنوان: |
Ventilator-Associated Pneumonia in Patients with COVID-19: A Systematic Review and Meta-Analysis. |
| المؤلفون: |
Ippolito, Mariachiara, Misseri, Giovanni, Catalisano, Giulia, Marino, Claudia, Ingoglia, Giulia, Alessi, Marta, Consiglio, Elisa, Gregoretti, Cesare, Giarratano, Antonino, Cortegiani, Andrea, Seki, Masafumi |
| المصدر: |
Antibiotics (2079-6382); May2021, Vol. 10 Issue 5, p545, 1p |
| مصطلحات موضوعية: |
COVID-19, VENTILATOR-associated pneumonia, INTENSIVE care patients, LENGTH of stay in hospitals |
| مستخلص: |
The aim of this systematic review and meta-analysis was to estimate the pooled occurrence of ventilator-associated pneumonia (VAP) among patients admitted to an intensive care unit with COVID-19 and mortality of those who developed VAP. We performed a systematic search on PubMed, EMBASE and Web of Science from inception to 2nd March 2021 for nonrandomized studies specifically addressing VAP in adult patients with COVID-19 and reporting data on at least one primary outcome of interest. Random effect single-arm meta-analysis was performed for the occurrence of VAP and mortality (at the longest follow up) and ICU length of stay. Twenty studies were included in the systematic review and meta-analysis, for a total of 2611 patients with at least one episode of VAP. The pooled estimated occurrence of VAP was of 45.4% (95% C.I. 37.8–53.2%; 2611/5593 patients; I2 = 96%). The pooled estimated occurrence of mortality was 42.7% (95% C.I. 34–51.7%; 371/946 patients; I2 = 82%). The estimated summary estimated metric mean ICU LOS was 28.58 days (95% C.I. 21.4–35.8; I2 = 98%). Sensitivity analysis showed that patients with COVID-19 may have a higher risk of developing VAP than patients without COVID-19 (OR 3.24; 95% C.I. 2.2–4.7; P = 0.015; I2 = 67.7%; five studies with a comparison group). [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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