Analysis of clinical features of neonates with congenital heart disease who develop necrotizing enterocolitis: a retrospective case-control study
| العنوان: | Analysis of clinical features of neonates with congenital heart disease who develop necrotizing enterocolitis: a retrospective case-control study |
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| المؤلفون: | Xiaolei, Gong, Xi, Chen, Liping, Wang, Mingjie, Zhang, Francesco, Nappi, Jeffrey D, Zampi, Jinghao, Zheng, Zhuoming, Xu, Nan, Bao |
| المصدر: | Annals of Translational Medicine. 10:879-879 |
| بيانات النشر: | AME Publishing Company, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | General Medicine |
| الوصف: | Infants with congenital heart disease (CHD) are known to have higher rates of necrotizing enterocolitis (NEC). Although the etiology is recognized as distinct from the premature neonatal population, there is not a universal consensus regarding etiology or specific risk factors. To analyze the clinical features of neonates with CHD who develop NEC.A retrospective study of neonates with CHD in the cardiac intensive care unit (ICU) between 2015 and 2018 was performed, and modified Bell's criteria were used to diagnose NEC. Patients were divided into 2 groups according to ductal-dependent (DD) lesions, and were further stratified by Risk Adjustment for Congenital Heart Surgery-1 (RACHS-1) score and Aristotle score, to compare the differences.Among 412 patients with CHD, 69 (16%) developed NEC. The incidence of NEC was notably higher among DD patients than among non-DD (nDD) patients (18.7%NEC is a common complication in neonates with CHD and can occur both before and after CHD operations. Likely there are varying mechanism for NEC in different forms of CHD. While NEC is more common in patients with DD CHD and those with more complex forms of CHD, there was no significant difference observed in weight-for-age Z-score (WAZ) between the DD group during follow-up. |
| تدمد: | 2305-5847 2305-5839 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a4214d6b10657c40fe95afedb95fa1Test https://doi.org/10.21037/atm-22-3248Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....43a4214d6b10657c40fe95afedb95fa1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23055847 23055839 |
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